Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.53 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.53 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.53 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.53 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.53 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | S100B | P04271 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2263257 | 1.00 | ALDH1A1 (0.58) | ALDH1A1CYP2A6CYP1A2GRIN2DGRIN3B | |
| SCHEMBL11776228 | 0.81 | GRIN2D (0.68) | ALDH1A1CYP2A6CYP1A2GRIN2DGRIN3B | |
| SCHEMBL269159 | 0.81 | GRIN2D (0.68) | ALDH1A1CYP2A6CYP1A2GRIN2DGRIN3B | |
| SCHEMBL11207836 | 0.79 | GRIN2D (0.55) | ALDH1A1CYP2A6CYP1A2GRIN2DGRIN3B | |
| SCHEMBL10374800 | 0.79 | GRIN2D (0.55) | ALDH1A1CYP2A6CYP1A2GRIN2DGRIN3B | |
| SCHEMBL7731054 | 0.78 | ALDH1A1 (0.54) | ALDH1A1CYP2A6CYP1A2GRIN2DGRIN3B | |
| SCHEMBL1963947 | 0.77 | GRIN2D (0.53) | ALDH1A1CYP2A6CYP1A2GRIN2DGRIN3B | |
| SCHEMBL3971293 | 0.77 | GRIN2D (0.58) | ALDH1A1CYP2A6CYP1A2GRIN2DGRIN3B | |
| SCHEMBL1566907 | 0.77 | KMT2A (0.69) | ALDH1A1CYP2A6CYP1A2GRIN2DGRIN3B | |
| SCHEMBL6077468 | 0.77 | GRIN2D (0.53) | ALDH1A1CYP2A6CYP1A2GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110201603-A1 | Novel Acylaminobenzamide Derivatives | BAYER CROPSCIENCE AG (DE) | 2011-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201603-A1 | Novel Acylaminobenzamide Derivatives | KCNB1, KCNA5, KCNA7 | ALDH1A1 271/4885CYP2A6 240/4885CYP1A2 126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.