SCHEMBL269159

SCHEMBL269159

COc1ccc(C=NN=Cc2ccc(OC)cc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 2/20 0.68
GRIN3B O60391 2/20 0.68
GRIN1 Q05586 2/20 0.68
GRIN2A Q12879 2/20 0.68
GRIN2B Q13224 2/20 0.68
GRIN2C Q14957 2/20 0.68
GRIN3A Q8TCU5 2/20 0.68
CHRM5 P08912 1/20 0.57
ALDH1A1 P00352 2/20 0.56
CYP2A6 P11509 1/20 0.56
CA12 O43570 1/20 0.55
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
CA7 P43166 1/20 0.55
CA9 Q16790 1/20 0.55
CA14 Q9ULX7 1/20 0.55
S100B P04271 1/20 0.55
SMN1; SMN2 Q16637 2/20 0.54
NPC1 O15118 1/20 0.54
RAB9A P51151 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11776228 1.00 GRIN2D (0.68) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL7616145 0.91 TRPA1 (0.67) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL7792584 0.89 NFE2L2 (0.68) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL7792580 0.89 NFE2L2 (0.68) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL16275197 0.89 S100B (0.71) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL12765874 0.87 GRIN2D (0.59) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL13939540 0.87 GRIN2D (0.59) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL22198149 0.86 POLB (0.56) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL22198299 0.86 GRIN2D (0.54) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL7791911 0.84 CYP1A1 (0.54) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210349035-A1 PATHOGEN MONITORING PLATYPUS TECHNOLOGIES, LLC 2021-11-11 US disclosed
US-20210318231-A1 Liquid Crystal-Based Detection of Air Contaminants Using Metal Surfaces NATIONAL SCIENCE FOUNDATION 2021-10-14 US disclosed
US-10928306-B2 Functional surfaces for liquid crystal-based detection of chlorine gas WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2021-02-23 US disclosed
US-20190212254-A1 Functional Surfaces for Liquid Crystal-Based Detection of Chlorine Gas NATIONAL SCIENCE FOUNDATION 2019-07-11 US disclosed
US-20180052111-A1 SUBSTRATES, DEVICES, AND METHODS FOR QUANTITATIVE LIQUID CRYSTAL ASSAYS PLATYPUS TECHNOLOGIES, LLC 2018-02-22 US disclosed
US-20180052111-A1 SUBSTRATES, DEVICES, AND METHODS FOR QUANTITATIVE LIQUID CRYSTAL ASSAYS PLATYPUS TECHNOLOGIES, LLC 2018-02-22 US disclosed
US-9816147-B2 Liquid crystal based analyte detection PLATYPUS TECHNOLOGIES, LLC (US) 2017-11-14 US disclosed
US-9816147-B2 Liquid crystal based analyte detection PLATYPUS TECHNOLOGIES, LLC (US) 2017-11-14 US disclosed
US-20170212088-A1 DETECTION OF GAS-PHASE ANALYTES USING LIQUID CRYSTALS PLATYPUS TECHNOLOGIES, LLC 2017-07-27 US disclosed
US-20170212088-A1 DETECTION OF GAS-PHASE ANALYTES USING LIQUID CRYSTALS PLATYPUS TECHNOLOGIES, LLC 2017-07-27 US disclosed
US-20070042505-A1 Liquid crystal based analyte detection PLATYPUS TECHNOLOGIES, LLC (US) 2007-02-22 US disclosed
US-20070004046-A1 Detection of analytes PLATYPUS TECHNOLOGIES, LLC (US) 2007-01-04 US disclosed
US-20070004046-A1 Detection of analytes PLATYPUS TECHNOLOGIES, LLC (US) 2007-01-04 US disclosed
EP-0736526-B1 Pyrazolidine derivative, radical scavenger, brain-infarction depressant, and brain-edema depressant SHISEIDO CO LTD (JP) 2003-02-12 EP disclosed
US-5849930-A Pyrazolidine derivative radical scavenger brain-infarction depressant and brain-edema depressant SHISEIDO CO., LTD. (JP) 1998-12-15 US disclosed
EP-0736526-A1 Pyrazolidine derivative, radical scavenger, brain-infarction depressant, and brain-edema depressant SHISEIDO COMPANY LIMITED (JP) 1996-10-09 EP disclosed
US-4012434-A Nematic compounds and mixtures MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1977-03-15 US disclosed
US-4002670-A 4'-ALKOXY OR ALKYL PHENYL ESTERS OF 4-ALKYL OR ALKOXY BENZOIC ACIDS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1977-01-11 US disclosed
US-4001137-A Nematic compounds and mixtures MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1977-01-04 US disclosed
US-3939147-A Novel 1,2-diaza-1,5,9-cyclo dodecatrienes and 1,2-diaza-1-cyclododecenes CIBA-GEIGY CORPORATION (US) 1976-02-17 US disclosed