SCHEMBL2263508

SCHEMBL2263508

Cc1ccc(C(=O)c2ccc(N(C)C)cc2)cc1

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.83
MAPT P10636 6/20 0.83
HPGD P15428 3/20 0.83
NPC1 O15118 4/20 0.70
RAB9A P51151 3/20 0.70
LMNA P02545 2/20 0.70
TSHR P16473 2/20 0.65
SRD5A2 P31213 2/20 0.59
KDM4E B2RXH2 3/20 0.57
HTT P42858 2/20 0.57
GAA P10253 1/20 0.53
SMN1; SMN2 Q16637 3/20 0.51
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
TP53 P04637 1/20 0.51
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
POLB P06746 2/20 0.49
NFKB1 P19838 1/20 0.49
NFKB2 Q00653 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12757184 0.94 ALDH1A1 (0.73) ALDH1A1MAPTHPGDNPC1RAB9A
SCHEMBL274966 0.91 ALDH1A1 (1.00) ALDH1A1MAPTHPGDNPC1RAB9A
Michler'S Ketone SCHEMBL36517 0.91 ALDH1A1 (1.00) ALDH1A1MAPTHPGDNPC1RAB9A
SCHEMBL12757106 0.89 ALDH1A1 (0.66) ALDH1A1MAPTHPGDNPC1RAB9A
SCHEMBL12757131 0.89 ALDH1A1 (0.66) ALDH1A1MAPTHPGDNPC1RAB9A
Michler'S Ketone SCHEMBL6566205 0.89 ALDH1A1 (0.95) ALDH1A1MAPTHPGDNPC1RAB9A
Michler'S Ketone SCHEMBL1396486 0.89 ALDH1A1 (0.95) ALDH1A1MAPTHPGDNPC1RAB9A
Michler'S Ketone SCHEMBL11758312 0.89 ALDH1A1 (0.95) ALDH1A1MAPTHPGDNPC1RAB9A
SCHEMBL12757158 0.87 ALDH1A1 (0.70) ALDH1A1MAPTHPGDNPC1RAB9A
SCHEMBL23951924 0.84 MAPT (0.86) ALDH1A1MAPTHPGDNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4555548-A Rubber composition for tire treads NIPPON ZEON CO. LTD. (JP) 1985-11-26 US claimed
US-4555547-A POLYBUTADIENE CONTAINING BENZOPHENONE OR THIOBENZOPHENONE UNITS INTHE CHAIN NIPPON ZEON CO. LTD. (JP) 1985-11-26 US claimed
JP-63139158-A None JP disclosed
EP-2666814-B1 ELECTRICALLY CONDUCTIVE RUBBER ELASTOMER, CHARGING MEMBER, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KK (JP) 2018-03-14 EP disclosed
US-20180016364-A1 LED-CURABLE LOW MIGRATION PHOTOINITIATORS IGM MALTA LIMITED (MT) 2018-01-18 US disclosed
US-9221855-B2 Thionation process and a thionating agent VIRONOVA THIONATION AB (SE) 2015-12-29 US disclosed
US-9115158-B2 Thionating agent VIRONOVA THIONATION AB (SE) 2015-08-25 US disclosed
US-9006458-B2 Surface Enhanced Raman Spectroscopy (SERS) compounds and methods of their preparation AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2015-04-14 US disclosed
EP-2490077-B1 ELECTRIFICATING MEMBER AND ELECTROPHOTOGRAPHIC DEVICE CANON KK (JP) 2014-10-01 EP disclosed
US-8750762-B2 Charging member with vulcanized rubber, and electrophotographic apparatus including the charging member CANON KABUSHIKI KAISHA (JP) 2014-06-10 US disclosed
EP-2666814-A1 ELECTRICALLY CONDUCTIVE RUBBER ELASTOMER, CHARGING MEMBER, AND ELECTROPHOTOGRAPHIC APPARATUS Canon Kabushiki Kaisha (JP) 2013-11-27 EP disclosed
US-5008238-A Thermosensitive material with phenolic developer RICOH COMPANY, LTD. (JP) 1991-04-16 US disclosed
US-4950719-A LOW TEMPERATURE VIBRATION INSULATOR NIPPON ZEON CO., LTD. (JP) 1990-08-21 US disclosed
US-4929679-A BUTADIENE-STYRENE COPOLYMERS BLENDS WITH NATURAL RUBBERS OR POLYISOPRENE, WEAR RESISTANCE NIPPON ZEON CO., LTD. (JP) 1990-05-29 US disclosed
US-4848511-A METALLIZED RUBBER MODIFIED WITH AMINE, THIOAMIDE, OR AMINE SUBSTITUTED (THIO) BENZOPHENONE NIPPON ZEON CO., LTD. (JP) 1989-07-18 US disclosed
JP-S63139158-A 4-DIMETHYLAMINOBENZOPHENONE DERIVATIVE KANEBO LTD 1988-06-10 JP disclosed
EP-0198295-A1 Vibration insulating rubber NIPPON ZEON CO., LTD. (JP) 1986-10-22 EP disclosed
US-4555548-A Rubber composition for tire treads NIPPON ZEON CO. LTD. (JP) 1985-11-26 US disclosed
US-4555547-A POLYBUTADIENE CONTAINING BENZOPHENONE OR THIOBENZOPHENONE UNITS INTHE CHAIN NIPPON ZEON CO. LTD. (JP) 1985-11-26 US disclosed
US-4264710-A AN ETHYLENICALLY UNSATURATED COMPOUND, AND A PHOTOPOLYMERIZATION INIATOR FUJI PHOTO FILM CO., LTD. (JP) 1981-04-28 US disclosed