SCHEMBL274966

SCHEMBL274966

CN(C)c1ccc(C(=O)c2ccc(C(=O)c3ccc(N(C)C)cc3)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 1.00
MAPT P10636 5/20 1.00
HPGD P15428 3/20 1.00
NPC1 O15118 4/20 0.83
RAB9A P51151 3/20 0.83
MEN1 O00255 4/20 0.58
KMT2A Q03164 4/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
TP53 P04637 1/20 0.58
TSHR P16473 3/20 0.58
ALOX15 P16050 2/20 0.58
HSD17B10 Q99714 1/20 0.58
MAPK1 P28482 2/20 0.56
CYP3A4 P08684 2/20 0.56
HBB P68871 1/20 0.56
POLB P06746 3/20 0.55
KDM4E B2RXH2 2/20 0.55
HDAC1 Q13547 2/20 0.55
HDAC6 Q9UBN7 2/20 0.55
LMNA P02545 4/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Michler'S Ketone SCHEMBL36517 1.00 ALDH1A1 (1.00) ALDH1A1MAPTHPGDNPC1RAB9A
Michler'S Ketone SCHEMBL1396486 0.97 ALDH1A1 (0.95) ALDH1A1MAPTHPGDNPC1RAB9A
Michler'S Ketone SCHEMBL6566205 0.97 ALDH1A1 (0.95) ALDH1A1MAPTHPGDNPC1RAB9A
Michler'S Ketone SCHEMBL11758312 0.97 ALDH1A1 (0.95) ALDH1A1MAPTHPGDNPC1RAB9A
SCHEMBL23951924 0.93 MAPT (0.86) ALDH1A1MAPTHPGDNPC1RAB9A
SCHEMBL12757189 0.93 ALDH1A1 (0.86) ALDH1A1MAPTHPGDNPC1RAB9A
Michler'S Ketone SCHEMBL3324670 0.91 HPGD (1.00) ALDH1A1MAPTHPGDNPC1RAB9A
SCHEMBL1309237 0.91 MAPT (0.83) ALDH1A1MAPTHPGDNPC1RAB9A
SCHEMBL2263508 0.91 ALDH1A1 (0.83) ALDH1A1MAPTHPGDNPC1RAB9A
SCHEMBL43585 0.91 HPGD (1.00) ALDH1A1MAPTHPGDNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0372778-A1 Photoinitiator Polychrome Corporation (US) 1990-06-13 EP claimed
JP-2194003-A None JP disclosed
EP-1403710-B1 Polymerizable composition FUJIFILM CORP (JP) 2015-06-10 EP disclosed
EP-2085220-B1 Resin composition for laser engraving, relief printing plate precursor for laser engraving, relief printing plate and method of producing the same FUJIFILM CORP (JP) 2015-05-20 EP disclosed
US-8822126-B2 Resin composition for laser engraving, relief printing plate precursor for laser engraving, relief printing plate, and method of manufacturing relief printing plate FUJIFILM CORPORATION (JP) 2014-09-02 US disclosed
US-8822126-B2 Resin composition for laser engraving, relief printing plate precursor for laser engraving, relief printing plate, and method of manufacturing relief printing plate FUJIFILM CORPORATION (JP) 2014-09-02 US disclosed
US-8669040-B2 Method of manufacturing relief printing plate and printing plate precursor for laser engraving FUJIFILM CORPORATION (JP) 2014-03-11 US disclosed
US-8669040-B2 Method of manufacturing relief printing plate and printing plate precursor for laser engraving FUJIFILM CORPORATION (JP) 2014-03-11 US disclosed
US-8389198-B2 Resin composition for laser engraving, resin printing plate precursor for laser engraving, relief printing plate and method for production of relief printing plate FUJIFILM CORPORATION (JP) 2013-03-05 US disclosed
US-8389198-B2 Resin composition for laser engraving, resin printing plate precursor for laser engraving, relief printing plate and method for production of relief printing plate FUJIFILM CORPORATION (JP) 2013-03-05 US disclosed
US-20070212883-A1 Method For Forming Surface Graft, Method For Forming Conductive Film, Method For Forming Method Pattern, Method For Forming Multilayer Wiring Board, Surface Graft Material, And Conductive Material FUJIFILM CORPORATION (JP) 2007-09-13 US disclosed
US-7232644-B2 Polymerizable composition and negative-working planographic printing plate precursor using the same FUJIFILM CORPORATION (JP) 2007-06-19 US disclosed
US-7232644-B2 Polymerizable composition and negative-working planographic printing plate precursor using the same FUJIFILM CORPORATION (JP) 2007-06-19 US disclosed
US-20070072113-A1 Photosensitive composition, and lithographic printing plate precursor and image-recording method using the same FUJI PHOTO FILM CO., LTD. 2007-03-29 US disclosed
US-20070072113-A1 Photosensitive composition, and lithographic printing plate precursor and image-recording method using the same FUJI PHOTO FILM CO., LTD. 2007-03-29 US disclosed
US-7179582-B2 Radical polymerizable composition and lithographic printing plate precursor using the same FUJI PHOTO FILM CO., LTD. (JP) 2007-02-20 US disclosed
US-7179582-B2 Radical polymerizable composition and lithographic printing plate precursor using the same FUJI PHOTO FILM CO., LTD. (JP) 2007-02-20 US disclosed
JP-H02194003-A PHOTOCROSS-LINKABLE COMPOSITION AND ITS PRODUCTION POLYCHROME CORP 1990-07-31 JP disclosed
EP-0372778-A1 Photoinitiator Polychrome Corporation (US) 1990-06-13 EP disclosed
EP-0371723-A2 Photocurable compositions and methods Polychrome Corporation (US) 1990-06-06 EP disclosed