Michler'S Ketone

Michler'S Ketone

SCHEMBL36517

CN(C)c1ccc(C(=O)c2ccc(N(C)C)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 1.00
MAPT P10636 5/20 1.00
HPGD P15428 3/20 1.00
NPC1 O15118 4/20 0.83
RAB9A P51151 3/20 0.83
MEN1 O00255 4/20 0.58
KMT2A Q03164 4/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
TP53 P04637 1/20 0.58
TSHR P16473 3/20 0.58
ALOX15 P16050 2/20 0.58
HSD17B10 Q99714 1/20 0.58
MAPK1 P28482 2/20 0.56
CYP3A4 P08684 2/20 0.56
HBB P68871 1/20 0.56
POLB P06746 3/20 0.55
KDM4E B2RXH2 2/20 0.55
HDAC1 Q13547 2/20 0.55
HDAC6 Q9UBN7 2/20 0.55
LMNA P02545 4/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL274966 1.00 ALDH1A1 (1.00) ALDH1A1MAPTHPGDNPC1RAB9A
Michler'S Ketone SCHEMBL1396486 0.97 ALDH1A1 (0.95) ALDH1A1MAPTHPGDNPC1RAB9A
Michler'S Ketone SCHEMBL6566205 0.97 ALDH1A1 (0.95) ALDH1A1MAPTHPGDNPC1RAB9A
Michler'S Ketone SCHEMBL11758312 0.97 ALDH1A1 (0.95) ALDH1A1MAPTHPGDNPC1RAB9A
SCHEMBL23951924 0.93 MAPT (0.86) ALDH1A1MAPTHPGDNPC1RAB9A
SCHEMBL12757189 0.93 ALDH1A1 (0.86) ALDH1A1MAPTHPGDNPC1RAB9A
Michler'S Ketone SCHEMBL3324670 0.91 HPGD (1.00) ALDH1A1MAPTHPGDNPC1RAB9A
SCHEMBL1309237 0.91 MAPT (0.83) ALDH1A1MAPTHPGDNPC1RAB9A
SCHEMBL2263508 0.91 ALDH1A1 (0.83) ALDH1A1MAPTHPGDNPC1RAB9A
SCHEMBL43585 0.91 HPGD (1.00) ALDH1A1MAPTHPGDNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 32191 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260132314-A1 ADHESIVE TAPE ETERNAL MATERIALS CO., LTD. (TW) 2026-05-14 US claimed
EP-4739648-A1 PHOTOISOMERIZATION OF GERANIAL AND NERAL BASF SE (DE) 2026-05-13 EP claimed
CN-122011834-A UV-LED curing offset printing ink, preparation method and application thereof 康达新材料(集团)股份有限公司 2026-05-12 CN claimed
CN-122025791-A Preparation method of double lithium salt type gel polymer electrolyte membrane 天津科技大学 2026-05-12 CN claimed
EP-4734894-A2 POLYMER COMPOSITIONS AND USES THEREOF The University of Melbourne (AU) 2026-05-06 EP claimed
WO-2025006821-A9 POLYMER COMPOSITIONS AND USES THEREOF THE UNIVERSITY OF MELBOURNE (AU) 2026-04-30 WO claimed
EP-3864072-B1 DUAL CURABLE ORGANOPOLYSILOXANE COMPOSITION DOW SILICONES CORP (US) 2026-01-28 EP claimed
EP-4455168-B1 VISIBLE LIGHT CURABLE COMPOSITION AND VISIBLE LIGHT CURABLE COMPOSITION POLYMERIZATION METHOD CHT TURKEY KIMYA SANAYI VE TICARET A S (TR) 2025-12-24 EP claimed
US-12459193-B2 Method and kit for non-destructive in situ repair (relining) of deteriorated pipelines APPLIED RESIN S L (ES) 2025-11-04 US claimed
EP-3916033-B1 ONE COMPONENT (1K) COMPOSITION BASED ON EPOXY RESIN HENKEL AG & CO KGAA (DE) 2025-10-29 EP claimed
US-4050941-A PHOTORESISTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-09-27 US claimed
US-4045223-A Method for the preparation of layer structures SIEMENS AKTIENGESELLSCHAFT (DT) 1977-08-30 US claimed
US-4025348-A DI-UNSATURATED COMPOUND, POLYMER WITH TETRAHYDROFURFURYL OR N-ALKOXYMETHYLCARBAMOYL GROUPS, DIEPOXIDE, SENSITIZER, CURING AGENT HITACHI CHEMICAL COMPANY, LTD. (JA) 1977-05-24 US claimed
US-4017313-A Photosensitive composition containing a leuco dye, a photosensitizer, an aromatic aldehyde and a secondary or tertiary amine and the use thereof in a direct-print process E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-04-12 US claimed
US-4017476-A Preparation of finely divided styrene-divinylbenzene organic pigments MOBIL OIL CORPORATION (US) 1977-04-12 US claimed
US-3983564-A Image recording member CANON KABUSHIKI KAISHA (JA) 1976-09-28 US claimed
US-3960685-A Photosensitive resin composition containing pullulan or esters thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-06-01 US claimed
US-RE28789-E ETHYLENICALLY UNSATURATED MONOMER; RADIATION ABSORBER E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-04-27 US claimed
US-3953309-A PHOTORESISTS DYNACHEM CORPORATION (US) 1976-04-27 US claimed
US-3932356-A UNSATURATED POLYETHERESTER CONTAINING GLYCIDYL (METH)ACRYLATE OR ALLYL GLYCIDYL ETHER RESIDUES KANSAI PAINT COMPANY, LTD. (JA) 1976-01-13 US claimed