Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | CASP1 | P29466 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.57 |
| ▸ | CASP7 | P55210 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL490325 | 0.86 | MAPK1 (0.44) | MAPK1ALDH1A1TSHRHSD17B10CASP1 | |
| SCHEMBL454197 | 0.76 | ALDH1A1 (0.61) | MAPK1ALDH1A1TSHRHSD17B10CASP1 | |
| Benzo(K)Fluoranthene SCHEMBL29393074 | 0.74 | ALDH1A1 (1.00) | MAPK1ALDH1A1TSHRHSD17B10CASP1 | |
| Benzo(K)Fluoranthene SCHEMBL175484 | 0.74 | ALDH1A1 (1.00) | MAPK1ALDH1A1TSHRHSD17B10CASP1 | |
| SCHEMBL2414392 | 0.73 | — | — | |
| SCHEMBL18221915 | 0.73 | ALDH1A1 (0.31) | ALDH1A1HSD17B10HPGD | |
| SCHEMBL2409154 | 0.73 | — | — | |
| SCHEMBL2413972 | 0.73 | ALDH1A1 (0.32) | MAPK1ALDH1A1TSHRHSD17B10L3MBTL1 | |
| SCHEMBL2409240 | 0.73 | ALDH1A1 (0.32) | MAPK1ALDH1A1TSHRHSD17B10L3MBTL1 | |
| SCHEMBL25401444 | 0.73 | ALDH1A1 (0.33) | MAPK1ALDH1A1TSHRHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111094223-B | binaphthyl compounds | 罗伊特化学仪器制造公司 | 2023-10-27 | — | — | CN | disclosed |
| US-11072573-B2 | Binaphthyl compounds | REUTER CHEMISCHE APPARATEBAU E.K. (DE) | 2021-07-27 | — | — | US | disclosed |
| US-20200354299-A1 | BINAPHTHYL COMPOUNDS | REUTER CHEMISCHE APPARATEBAU E.K. (DE) | 2020-11-12 | — | — | US | disclosed |
| CN-111094223-A | Binaphthyl compounds | 罗伊特化学仪器制造公司 | 2020-05-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200354299-A1 | BINAPHTHYL COMPOUNDS | UACA, C9, C1S | MAPK1 4149/4885ALDH1A1 1476/4885TSHR 3380/4885 |
| US-11072573-B2 | Binaphthyl compounds | UACA, C9, C1S | MAPK1 4149/4885ALDH1A1 1476/4885TSHR 3380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.