Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | SLC16A3 | O15427 | 7/20 | 0.64 |
| ▸ | SLC16A1 | P53985 | 7/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22635882 | 1.00 | KDM4E (0.66) | KDM4ELMNAPKMKMT2ASLC16A3 | |
| SCHEMBL9360940 | 0.84 | CYP1A2 (0.78) | KDM4ELMNAPKMKMT2ASLC16A3 | |
| SCHEMBL9658963 | 0.84 | PKM (0.68) | KDM4ELMNAPKMKMT2ASLC16A3 | |
| SCHEMBL9658958 | 0.84 | PKM (0.68) | KDM4ELMNAPKMKMT2ASLC16A3 | |
| SCHEMBL17831051 | 0.84 | KDM4E (0.68) | KDM4ELMNAPKMKMT2ASLC16A3 | |
| SCHEMBL8649661 | 0.84 | CYP1A2 (0.78) | KDM4ELMNAPKMKMT2ASLC16A3 | |
| SCHEMBL15740335 | 0.80 | KDM4E (1.00) | KDM4ELMNAPKMKMT2ASLC16A3 | |
| SCHEMBL15740336 | 0.80 | KDM4E (1.00) | KDM4ELMNAPKMKMT2ASLC16A3 | |
| SCHEMBL22635876 | 0.79 | CYP1A2 (0.48) | KDM4ELMNAPKMKMT2ASLC16A3 | |
| SCHEMBL15129031 | 0.78 | SLC16A3 (0.79) | KDM4ELMNAPKMKMT2ASLC16A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020225386-A1 | 3-(4-AMINO-2-METHOXYPHENYL)-2-CYANOACRYLIC ACID DERIVATIVES AND THE USE OF SAME AS PRECURSORS FOR THE PREPARATION OF RADIOCHEMICAL COMPOUNDS | HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF E.V. (DE) | 2020-11-12 | — | — | WO | disclosed |
| WO-2020225386-A1 | 3-(4-AMINO-2-METHOXYPHENYL)-2-CYANOACRYLIC ACID DERIVATIVES AND THE USE OF SAME AS PRECURSORS FOR THE PREPARATION OF RADIOCHEMICAL COMPOUNDS | HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF E.V. (DE) | 2020-11-12 | — | — | WO | disclosed |