SCHEMBL22636714

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29430620	1.00	MAPK1 (0.44)	MAPK1TP53FYNTDO2TAAR1
	SCHEMBL22637149	0.86	TDO2 (0.51)	MAPK1TDO2L3MBTL1PDE3BPDE3A
	SCHEMBL29430767	0.86	TDO2 (0.51)	MAPK1TDO2L3MBTL1PDE3BPDE3A
	SCHEMBL22637054	0.81	TDO2 (0.56)	TP53TDO2PDE3BPDE3AMAPT
	SCHEMBL29430584	0.81	TDO2 (0.56)	TP53TDO2PDE3BPDE3AMAPT
	SCHEMBL22637035	0.76	BRD4 (0.37)	MAPK1TDO2L3MBTL1MAPTBRD4
	SCHEMBL31198523	0.76	MAP4K4 (0.53)	TDO2L3MBTL1MAPTSMN1; SMN2MEN1
	SCHEMBL17532994	0.76	TDO2 (0.66)	TP53FYNTDO2TAAR1L3MBTL1
	SCHEMBL22648191	0.76	TAAR1 (0.41)	MAPK1FYNTDO2TAAR1PDE3B
	SCHEMBL22636845	0.75	TDO2 (0.55)	MAPK1TP53TDO2L3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.