Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22633972 | 0.79 | MEN1 (0.56) | GAAALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL22638051 | 0.78 | ALDH1A1 (0.43) | GAAALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL22633990 | 0.78 | KMT2A (0.45) | GAAALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL22633969 | 0.77 | MEN1 (0.55) | GAAALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL28913363 | 0.77 | ALDH1A1 (0.51) | GAAALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL22634089 | 0.76 | ALDH1A1 (0.48) | GAAALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL5542522 | 0.75 | RAB9A (0.71) | GAAALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL11530550 | 0.74 | ALDH1A1 (0.61) | GAAALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL1407285 | 0.74 | ALDH1A1 (0.49) | GAAALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL29554003 | 0.74 | ALDH1A1 (0.49) | GAAALDH1A1KDM4EMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020227592-A1 | THIOSEMICARBAZATES AND USES THEREOF | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2020-11-12 | — | — | WO | disclosed |