Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28913363 | 0.82 | ALDH1A1 (0.51) | MEN1KMT2AL3MBTL1CYP1A2KDM4E | |
| SCHEMBL1512585 | 0.81 | MEN1 (0.62) | MEN1KMT2AL3MBTL1CYP1A2KDM4E | |
| SCHEMBL11393946 | 0.80 | KMT2A (0.55) | MEN1KMT2AL3MBTL1CYP1A2KDM4E | |
| SCHEMBL22638009 | 0.79 | GAA (0.50) | MEN1KMT2AL3MBTL1CYP1A2KDM4E | |
| SCHEMBL11530550 | 0.78 | ALDH1A1 (0.61) | MEN1KMT2AL3MBTL1CYP1A2KDM4E | |
| SCHEMBL11817094 | 0.76 | MEN1 (0.79) | MEN1KMT2AL3MBTL1KDM4EMAPT | |
| SCHEMBL30423816 | 0.76 | MEN1 (0.79) | MEN1KMT2AL3MBTL1KDM4EMAPT | |
| SCHEMBL11403202 | 0.76 | LMNA (0.53) | MEN1KMT2AL3MBTL1CYP1A2KDM4E | |
| SCHEMBL17690051 | 0.75 | ALDH1A1 (0.58) | MEN1KMT2AL3MBTL1CYP1A2KDM4E | |
| SCHEMBL22649378 | 0.75 | ALDH1A1 (0.58) | MEN1KMT2AL3MBTL1CYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200354318-A1 | THIOSEMICARBAZATES AND USES THEREOF | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2020-11-12 | — | — | US | disclosed |
| WO-2020227592-A1 | THIOSEMICARBAZATES AND USES THEREOF | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2020-11-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200354318-A1 | THIOSEMICARBAZATES AND USES THEREOF | TST, ABAT, AADAC | MEN1 850/4885KMT2A 1523/4885L3MBTL1 757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.