Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 1.00 |
| ▸ | NPC1 | O15118 | 7/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 1.00 |
| ▸ | POLB | P06746 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 5/20 | 0.88 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.88 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | PPARG | P37231 | 1/20 | 0.57 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1622809 | 1.00 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2RXFP1POLB | |
| SCHEMBL13597998 | 0.84 | KMT2A (0.82) | RAB9ANPC1SMN1; SMN2RXFP1POLB | |
| SCHEMBL5529629 | 0.83 | NPC1 (0.71) | RAB9ANPC1SMN1; SMN2RXFP1POLB | |
| SCHEMBL13598070 | 0.83 | NPC1 (0.71) | RAB9ANPC1SMN1; SMN2RXFP1POLB | |
| SCHEMBL7444121 | 0.83 | NPC1 (0.71) | RAB9ANPC1SMN1; SMN2RXFP1POLB | |
| SCHEMBL7435902 | 0.81 | KMT2A (0.72) | RAB9ANPC1SMN1; SMN2RXFP1POLB | |
| SCHEMBL4698095 | 0.81 | NPC1 (0.68) | RAB9ANPC1SMN1; SMN2RXFP1POLB | |
| SCHEMBL24130834 | 0.79 | RAB9A (0.66) | RAB9ANPC1SMN1; SMN2RXFP1POLB | |
| SCHEMBL13597989 | 0.79 | NPC1 (0.65) | RAB9ANPC1SMN1; SMN2RXFP1POLB | |
| SCHEMBL1395840 | 0.79 | KDM4E (0.98) | RAB9ANPC1SMN1; SMN2RXFP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10828281-B2 | Non-hydrophobic compounds for use in treating metastasis and/or cartilage defect | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2020-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10828281-B2 | Non-hydrophobic compounds for use in treating metastasis and/or cartilage defect | VIM, MATR3, TP53 | RAB9A 2614/4885NPC1 475/4885SMN1; SMN2 2515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.