Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.97 |
| ▸ | MEN1 | O00255 | 3/20 | 0.97 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.59 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.59 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16392433 | 1.00 | KMT2A (0.97) | KMT2AMEN1ABCB1HSD17B10SMN1; SMN2 | |
| SCHEMBL16392429 | 0.90 | KMT2A (0.80) | KMT2AMEN1ABCB1HSD17B10SMN1; SMN2 | |
| SCHEMBL21067488 | 0.90 | KMT2A (0.80) | KMT2AMEN1ABCB1HSD17B10SMN1; SMN2 | |
| SCHEMBL22639949 | 0.87 | KMT2A (0.75) | KMT2AMEN1ABCB1SMN1; SMN2MAPT | |
| SCHEMBL22640040 | 0.87 | KMT2A (0.75) | KMT2AMEN1ABCB1SMN1; SMN2MAPT | |
| SCHEMBL7282006 | 0.85 | KMT2A (0.72) | KMT2AMEN1ABCB1HSD17B10SMN1; SMN2 | |
| SCHEMBL16370541 | 0.84 | LMNA (0.82) | KMT2AMEN1ABCB1SMN1; SMN2MAPT | |
| SCHEMBL22640107 | 0.84 | LMNA (0.82) | KMT2AMEN1ABCB1SMN1; SMN2MAPT | |
| SCHEMBL22640057 | 0.83 | KMT2A (0.69) | KMT2AMEN1ABCB1HSD17B10SMN1; SMN2 | |
| SCHEMBL22639703 | 0.83 | KMT2A (0.69) | KMT2AMEN1ABCB1HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10828281-B2 | Non-hydrophobic compounds for use in treating metastasis and/or cartilage defect | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2020-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10828281-B2 | Non-hydrophobic compounds for use in treating metastasis and/or cartilage defect | VIM, MATR3, TP53 | KMT2A 4613/4885MEN1 935/4885ABCB1 265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.