Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.72 |
| ▸ | MEN1 | O00255 | 3/20 | 0.72 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22639949 | 0.87 | KMT2A (0.75) | KMT2AMEN1MAPTSMN1; SMN2TP53 | |
| SCHEMBL22640040 | 0.87 | KMT2A (0.75) | KMT2AMEN1MAPTSMN1; SMN2TP53 | |
| SCHEMBL22639797 | 0.85 | KMT2A (0.97) | KMT2AMEN1MAPTSMN1; SMN2TP53 | |
| SCHEMBL16392433 | 0.85 | KMT2A (0.97) | KMT2AMEN1MAPTSMN1; SMN2TP53 | |
| SCHEMBL22640144 | 0.84 | LMNA (0.82) | KMT2AMEN1MAPTSMN1; SMN2LMNA | |
| SCHEMBL7289695 | 0.84 | LMNA (0.82) | KMT2AMEN1MAPTSMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL11619915 | 0.83 | KMT2A (0.80) | KMT2AMEN1MAPTSMN1; SMN2LMNA | |
| SCHEMBL6754439 | 0.81 | USP2 (0.81) | KMT2AMEN1MAPTPOLBUSP2 | |
| SCHEMBL24322624 | 0.80 | L3MBTL1 (0.72) | KMT2AMEN1MAPTSMN1; SMN2TP53 | |
| SCHEMBL11121575 | 0.79 | KMT2A (0.61) | KMT2AMEN1MAPTSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4567264-A | ADRENERGIC BLOCKING AGENTS | SYNTEX (U.S.A.) INC. (US) | 1986-01-28 | — | — | US | disclosed |
| EP-0126449-A1 | Cardioselective aryloxy- and arylthio-hydroxypropyl piperazinyl acetanilides wich affect calcium entry | SYNTEX (U.S.A.) INC. (US) | 1984-11-28 | — | — | EP | disclosed |