Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.80 |
| ▸ | MEN1 | O00255 | 3/20 | 0.80 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.76 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.59 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.59 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16392429 | 1.00 | KMT2A (0.80) | KMT2AMEN1HSD17B10ABCB1L3MBTL1 | |
| SCHEMBL22639797 | 0.90 | KMT2A (0.97) | KMT2AMEN1HSD17B10ABCB1L3MBTL1 | |
| SCHEMBL16392433 | 0.90 | KMT2A (0.97) | KMT2AMEN1HSD17B10ABCB1L3MBTL1 | |
| SCHEMBL22640107 | 0.84 | LMNA (0.82) | KMT2AMEN1ABCB1L3MBTL1ADRB2 | |
| SCHEMBL16370541 | 0.84 | LMNA (0.82) | KMT2AMEN1ABCB1L3MBTL1ADRB2 | |
| SCHEMBL12834994 | 0.81 | USP2 (0.81) | KMT2AMEN1ABCB1L3MBTL1SMN1; SMN2 | |
| SCHEMBL16370581 | 0.81 | L3MBTL1 (0.71) | KMT2AMEN1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL16371024 | 0.81 | L3MBTL1 (0.71) | KMT2AMEN1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL16370714 | 0.81 | L3MBTL1 (0.71) | KMT2AMEN1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL13838477 | 0.80 | MAPT (0.84) | KMT2AMEN1ABCB1L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |