Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 1/20 | 0.63 |
| ▸ | HTR2C | P28335 | 2/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NSD2 | O96028 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | PARG | Q86W56 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | GBA1 | P04062 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27900201 | 0.85 | CCR8 (0.53) | CCR8ALDH1A1MAPK1SMN1; SMN2PKM | |
| SCHEMBL28528621 | 0.82 | HTR2C (0.60) | CCR8HTR2CALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL16371501 | 0.79 | NSD2 (0.59) | CCR8ALDH1A1SMN1; SMN2NSD2PKM | |
| SCHEMBL24997782 | 0.78 | CCR8 (1.00) | CCR8 | |
| SCHEMBL16372049 | 0.78 | MEN1 (0.59) | CCR8ALDH1A1SMN1; SMN2NSD2PKM | |
| SCHEMBL22640128 | 0.77 | NSD2 (0.54) | CCR8ALDH1A1NSD2MEN1KMT2A | |
| SCHEMBL14419602 | 0.76 | PARG (0.55) | CCR8HTR2CALDH1A1SMN1; SMN2HTR2B | |
| SCHEMBL14834130 | 0.76 | MGLL (0.74) | CCR8ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL14819973 | 0.73 | ALDH1A1 (0.68) | CCR8ALDH1A1SMN1; SMN2NSD2PKM | |
| SCHEMBL31586351 | 0.71 | HTR2C (0.56) | CCR8HTR2CALDH1A1SMN1; SMN2HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10828281-B2 | Non-hydrophobic compounds for use in treating metastasis and/or cartilage defect | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2020-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10828281-B2 | Non-hydrophobic compounds for use in treating metastasis and/or cartilage defect | VIM, MATR3, TP53 | CCR8 685/4885HTR2C 3481/4885HTR2A 3340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.