Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.46 |
| ▸ | USP9X | Q93008 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27917796 | 0.86 | ALDH1A1 (0.68) | ALDH1A1KMT2AMEN1CYP2C9PKM | |
| SCHEMBL22639972 | 0.85 | CCR8 (0.63) | CCR8ALDH1A1KMT2AMEN1PKM | |
| SCHEMBL27917785 | 0.84 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1CYP2C9TGFBR1 | |
| SCHEMBL27917918 | 0.83 | MGLL (0.51) | CCR8ALDH1A1KMT2AMEN1CYP2C9 | |
| SCHEMBL27917838 | 0.82 | BCHE (0.65) | ALDH1A1TGFBR1PKMLMNAGBA1 | |
| SCHEMBL27917924 | 0.82 | ALDH1A1 (0.70) | ALDH1A1KMT2AMEN1TGFBR1PKM | |
| SCHEMBL14834137 | 0.81 | MGLL (0.65) | ALDH1A1KMT2AMEN1CYP2C9PKM | |
| SCHEMBL18446034 | 0.81 | HTR1A (0.54) | ALDH1A1KMT2AMEN1CYP2C9PKM | |
| SCHEMBL14834130 | 0.81 | MGLL (0.74) | CCR8ALDH1A1KMT2AMEN1TGFBR1 | |
| SCHEMBL27917786 | 0.81 | ALDH1A1 (0.62) | ALDH1A1TGFBR1PKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103068797-A | Hexafluoroisopropyl carbamate derivatives, their preparation and their therapeutic application | SANOFI SA | 2013-04-24 | — | — | CN | disclosed |