Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.77 |
| ▸ | GAA | P10253 | 1/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | AR | P10275 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24191085 | 0.72 | SCN9A (0.78) | KDM4EGAAALDH1A1LMNASCN9A | |
| SCHEMBL22640171 | 0.72 | RAB9A (0.61) | KDM4EALDH1A1MAPTTSHRLMNA | |
| SCHEMBL5114943 | 0.72 | AR (1.00) | ALDH1A1MAPTLMNANPC1TP53 | |
| SCHEMBL5112528 | 0.71 | AR (0.70) | ALDH1A1MAPTTSHRLMNANPC1 | |
| SCHEMBL25199199 | 0.70 | SCN9A (0.89) | KDM4ESCN9ASMN1; SMN2SCN5A | |
| SCHEMBL489736 | 0.69 | KMT2A (1.00) | TSHRLMNASCN9ARAB9AL3MBTL1 | |
| SCHEMBL15575015 | 0.69 | SCN9A (0.59) | KDM4EGAAALDH1A1LMNASCN9A | |
| SCHEMBL15707843 | 0.69 | SMN1; SMN2 (0.76) | GAAALDH1A1MAPTLMNANPC1 | |
| SCHEMBL3751093 | 0.68 | MAPT (0.53) | KDM4EGAAALDH1A1MAPTTSHR | |
| SCHEMBL5499447 | 0.68 | AR (0.67) | GAAALDH1A1MAPTTSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10828281-B2 | Non-hydrophobic compounds for use in treating metastasis and/or cartilage defect | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2020-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10828281-B2 | Non-hydrophobic compounds for use in treating metastasis and/or cartilage defect | VIM, MATR3, TP53 | KDM4E 4343/4885GAA 2575/4885ALDH1A1 1636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.