Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3743378 | 0.70 | MAPT (0.36) | MAPTTP53NPC1RAB9ALMNA | |
| SCHEMBL22640100 | 0.68 | KDM4E (0.77) | MAPTTP53NPC1RAB9ALMNA | |
| SCHEMBL29125692 | 0.66 | SMN1; SMN2 (0.43) | MAPTTP53NPC1RAB9ALMNA | |
| SCHEMBL5021587 | 0.65 | L3MBTL1 (0.50) | MAPTALDH1A1SMN1; SMN2KDM4EGAA | |
| SCHEMBL842961 | 0.65 | SCN9A (0.65) | MAPTNPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL22248702 | 0.64 | HRH3 (0.62) | TP53NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL20234326 | 0.64 | HRH3 (0.61) | MAPTTP53NPC1RAB9ALMNA | |
| SCHEMBL4902926 | 0.63 | SMN1; SMN2 (0.66) | MAPTTP53NPC1RAB9ALMNA | |
| SCHEMBL22248703 | 0.62 | HRH3 (0.65) | TP53NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL10928013 | 0.62 | SMN1; SMN2 (0.54) | MAPTTP53NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829575-B2 | Methods for treating androgen receptor related disorders | UNIVERSITY OF CINCINNATI (US) | 2010-11-09 | — | — | US | disclosed |
| US-20080015207-A1 | Methods for treating androgen receptor related disorders | CINCINNATI, UNIVERSITY OF | 2008-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080015207-A1 | Methods for treating androgen receptor related disorders | AR, SHBG, KLK3 | MAPT 2776/4885TP53 488/4885NPC1 4679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.