Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 3/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.52 |
| ▸ | PLAU | P00749 | 2/20 | 0.49 |
| ▸ | NMUR2 | Q9GZQ4 | 3/20 | 0.47 |
| ▸ | NMUR1 | Q9HB89 | 3/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.45 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.45 |
| ▸ | MC4R | P32245 | 1/20 | 0.45 |
| ▸ | MC3R | P41968 | 1/20 | 0.45 |
| ▸ | MC1R | Q01726 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22640189 | 0.96 | PLG (0.49) | PLGPRSS1PRSS2PRSS3PLAU | |
| SCHEMBL20228992 | 0.95 | PLG (0.51) | PLGPRSS1PRSS2PRSS3PLAU | |
| SCHEMBL22640195 | 0.93 | PLG (0.49) | PLGPRSS1PRSS2PRSS3NMUR2 | |
| SCHEMBL20228974 | 0.91 | PLG (0.45) | PLGPRSS1PRSS2PRSS3PLAU | |
| SCHEMBL20228972 | 0.91 | PLG (0.45) | PLGPRSS1PRSS2PRSS3PLAU | |
| SCHEMBL22640191 | 0.90 | KISS1R (0.46) | PLGPRSS1PRSS2PRSS3NMUR2 | |
| SCHEMBL20228991 | 0.85 | PLG (0.42) | PLGPRSS1PRSS2PRSS3NMUR2 | |
| SCHEMBL14527564 | 0.83 | CAPN1 (0.51) | PLGPRSS1PRSS2PRSS3NMUR2 | |
| SCHEMBL20228973 | 0.82 | KISS1R (0.41) | PLGPRSS1PRSS2PRSS3NMUR2 | |
| SCHEMBL14527599 | 0.81 | PLG (0.59) | PLGPRSS1PRSS2PRSS3PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10829516-B2 | Peptidomimetics for imaging the ghrelin receptor | LONDON HEALTH SCIENCES CENTRE RESEARCH INC. (CA) | 2020-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10829516-B2 | Peptidomimetics for imaging the ghrelin receptor | GHSR, GRPR, GHRHR | PLG 1365/4885PRSS1 1778/4885PRSS2 2216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.