Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 2/20 | 0.52 |
| ▸ | IKBKB | O14920 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | USP28 | Q96RU2 | 8/20 | 0.40 |
| ▸ | USP25 | Q9UHP3 | 6/20 | 0.40 |
| ▸ | SLC14A1 | Q13336 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24595746 | 0.87 | IKBKB (0.67) | LIMK1IKBKBMAPTRAB9ANPC1 | |
| SCHEMBL12562427 | 0.78 | LIMK1 (0.77) | LIMK1IKBKBMAPTRAB9ANPC1 | |
| SCHEMBL24248146 | 0.78 | THRB (0.47) | LIMK1IKBKBMAPTRAB9ANPC1 | |
| SCHEMBL24248149 | 0.77 | ALDH1A1 (0.42) | LIMK1IKBKBMAPTRAB9ANPC1 | |
| SCHEMBL14191227 | 0.76 | LIMK1 (0.50) | LIMK1IKBKBMAPTALDH1A1NPSR1 | |
| SCHEMBL25487830 | 0.75 | LIMK1 (0.35) | LIMK1IKBKBMAPTRAB9ANPC1 | |
| SCHEMBL22645007 | 0.75 | KDM4E (0.47) | LIMK1IKBKBMAPTRAB9ANPC1 | |
| SCHEMBL22644971 | 0.72 | ACACB (0.41) | LIMK1IKBKBUSP28USP25 | |
| SCHEMBL22644973 | 0.72 | ACACB (0.41) | LIMK1IKBKBUSP28USP25 | |
| SCHEMBL4126822 | 0.70 | IKBKB (0.52) | LIMK1IKBKBMAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224652-A1 | UBIQUITIN-SPECIFIC PROTEASE INHIBITORS, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 北京普济远成生物科技有限公司 | 2020-11-12 | — | — | WO | disclosed |