SCHEMBL22646141

SCHEMBL22646141

CCCCCCCCOC(=O)CCCCCCCN(CCCCCCCC(=O)OC(CCCCC)CCCCCC)CCCNc1c(N)c(=O)c1=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
GRIN2D O15399 1/20 0.40
GRIN3B O60391 1/20 0.40
GRIN1 Q05586 1/20 0.40
GRIN2A Q12879 1/20 0.40
GRIN2B Q13224 1/20 0.40
GRIN2C Q14957 1/20 0.40
GRIN3A Q8TCU5 1/20 0.40
TLR2 O60603 6/20 0.39
PRKCA P17252 1/20 0.38
PRKCE Q02156 1/20 0.38
PRKCQ Q04759 1/20 0.38
PRKCD Q05655 1/20 0.38
DNM1 Q05193 1/20 0.37
PRSS1 P07477 1/20 0.36
PRSS2 P07478 1/20 0.36
PRSS3 P35030 1/20 0.36
DGKA P23743 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20500789 1.00 ALDH1A1 (0.40) ALDH1A1LMNAGRIN2DGRIN3BGRIN1
SCHEMBL21806905 0.93 ALDH1A1 (0.43) ALDH1A1LMNATLR2PRKCAPRKCE
SCHEMBL21807015 0.92 GRIN2D (0.42) ALDH1A1LMNAGRIN2DGRIN3BGRIN1
SCHEMBL21807083 0.92 ALDH1A1 (0.42) ALDH1A1LMNATLR2PRKCAPRKCE
SCHEMBL21230937 0.91 ALDH1A1 (0.41) ALDH1A1LMNATLR2PRKCAPRKCE
SCHEMBL24372255 0.90 ALDH1A1 (0.40) ALDH1A1LMNATLR2PRKCAPRKCE
SCHEMBL22645923 0.90 ALDH1A1 (0.40) ALDH1A1LMNATLR2PRKCAPRKCE
SCHEMBL21461639 0.90 ALDH1A1 (0.40) ALDH1A1LMNATLR2PRKCAPRKCE
SCHEMBL20500800 0.90 ALDH1A1 (0.40) ALDH1A1LMNATLR2PRKCAPRKCE
SCHEMBL18641664 0.90 ALDH1A1 (0.40) ALDH1A1LMNATLR2PRKCAPRKCE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020227537-A1 DIFFERENTIALLY EXPRESSED IMMUNE CELL MICRORNAS FOR REGULATION OF PROTEIN EXPRESSION Modernatx, Inc (US) 2020-11-12 WO disclosed