SCHEMBL21461639

SCHEMBL21461639

CCCCCCCCCCCOC(=O)CCCCCN(CCCCCCCC(=O)OC(CCCCCCCC)CCCCCCCC)CCCNc1c(NC)c(=O)c1=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
PRKCA P17252 1/20 0.38
PRKCE Q02156 1/20 0.38
PRKCQ Q04759 1/20 0.38
PRKCD Q05655 1/20 0.38
DNM1 Q05193 1/20 0.38
DGKA P23743 1/20 0.37
MAPT P10636 1/20 0.37
MAPK1 P28482 1/20 0.37
TOP2A P11388 1/20 0.37
TLR2 O60603 1/20 0.36
PLA2G2A P14555 2/20 0.36
CNR1 P21554 1/20 0.35
CNR2 P34972 1/20 0.35
DAGLA Q9Y4D2 1/20 0.35
LPAR1 Q92633 2/20 0.35
LPAR3 Q9UBY5 2/20 0.35
ENPP2 Q13822 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29322918 1.00 ALDH1A1 (0.40) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL31065289 1.00 ALDH1A1 (0.40) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL31065316 1.00 ALDH1A1 (0.40) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL31065295 1.00 ALDH1A1 (0.40) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL18641664 1.00 ALDH1A1 (0.40) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL31065296 1.00 ALDH1A1 (0.40) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL31065317 1.00 ALDH1A1 (0.40) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL22645923 1.00 ALDH1A1 (0.40) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL20500800 1.00 ALDH1A1 (0.40) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL29322771 1.00 ALDH1A1 (0.40) ALDH1A1LMNAPRKCAPRKCEPRKCQ

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260069549-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX INC (US) 2026-03-12 US disclosed
EP-4186888-B1 COMPOUND AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX INC (US) 2025-11-26 EP disclosed
US-20250228777-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS ARES CAPITAL CORPORATION, AS AGENT 2025-07-17 US disclosed
US-12324859-B2 Compounds and compositions for intracellular delivery of therapeutic agents MODERNATX, INC. (US) 2025-06-10 US disclosed
US-12263248-B2 Compounds and compositions for intracellular delivery of therapeutic agents MODERNATX, INC. (US) 2025-04-01 US disclosed
WO-2024026482-A1 LIPID NANOPARTICLE COMPOSITIONS COMPRISING SURFACE LIPID DERIVATIVES AND RELATED USES MODERNATX, INC. (US) 2024-02-01 WO disclosed
US-11771715-B2 Circular RNA compositions and methods ORNA THERAPEUTICS, INC. (US) 2023-10-03 US disclosed
US-11771715-B2 Circular RNA compositions and methods ORNA THERAPEUTICS, INC. (US) 2023-10-03 US disclosed
US-11766449-B2 Circular RNA compositions and methods ORNA THERAPEUTICS, INC. (US) 2023-09-26 US disclosed
US-11766449-B2 Circular RNA compositions and methods ORNA THERAPEUTICS, INC. (US) 2023-09-26 US disclosed
US-20210154148-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS ARES CAPITAL CORPORATION, AS AGENT 2021-05-27 US disclosed
WO-2021076805-A1 MRNAS ENCODING IMMUNE MODULATING POLYPEPTIDES AND USES THEREOF Moderna TX, Inc. (US) 2021-04-22 WO disclosed
WO-2021026358-A1 COMPOSITIONS AND METHODS FOR ENHANCED DELIVERY OF AGENTS Moderna TX, Inc. (US) 2021-02-11 WO disclosed
US-10857105-B2 Compounds and compositions for intracellular delivery of therapeutic agents MordernaTX, Inc. (US) 2020-12-08 US disclosed
US-10857105-B2 Compounds and compositions for intracellular delivery of therapeutic agents MordernaTX, Inc. (US) 2020-12-08 US disclosed
WO-2020061367-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX, INC. (US) 2020-03-26 WO disclosed
WO-2020061367-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX, INC. (US) 2020-03-26 WO disclosed
US-20190314291-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS TO IMMUNE CELLS MODERNATX, INC. 2019-10-17 US disclosed
US-20190314292-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS ARES CAPITAL CORPORATION, AS AGENT 2019-10-17 US disclosed
US-20190314292-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS ARES CAPITAL CORPORATION, AS AGENT 2019-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12324859-B2 Compounds and compositions for intracellular delivery of therapeutic agents LNPK, PLTP, PLIN3 ALDH1A1 4530/4885LMNA 1539/4885PRKCA 1376/4885
US-20210154148-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS LNPK, PLTP, PLIN3 ALDH1A1 4530/4885LMNA 1539/4885PRKCA 1376/4885
US-11771715-B2 Circular RNA compositions and methods RTCB, HNRNPA1, HNRNPAB ALDH1A1 4484/4885LMNA 918/4885PRKCA 2758/4885
US-12263248-B2 Compounds and compositions for intracellular delivery of therapeutic agents LNPK, PLTP, PLIN3 ALDH1A1 4530/4885LMNA 1539/4885PRKCA 1376/4885
US-10857105-B2 Compounds and compositions for intracellular delivery of therapeutic agents LNPK, PLTP, PLIN3 ALDH1A1 4530/4885LMNA 1539/4885PRKCA 1376/4885
US-20260069549-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS SIN3A, PLIN3, MSR1 ALDH1A1 4755/4885LMNA 1487/4885PRKCA 1978/4885
US-20190314292-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS LNPK, PLTP, PLIN3 ALDH1A1 4530/4885LMNA 1539/4885PRKCA 1376/4885
US-20190314291-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS TO IMMUNE CELLS LCP2, CD14, MYD88 ALDH1A1 4722/4885LMNA 670/4885PRKCA 1620/4885
US-11766449-B2 Circular RNA compositions and methods RTCB, RNGTT, HNRNPAB ALDH1A1 4532/4885LMNA 1053/4885PRKCA 2331/4885
US-20250228777-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS LNPK, PLTP, PLIN3 ALDH1A1 4530/4885LMNA 1539/4885PRKCA 1376/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.