SCHEMBL24372255

SCHEMBL24372255

CCCCCCCCCOC(=O)CCCCCCCN(CCCCCCCC(=O)OC(CCCCCCCC)CCCCCCCC)CCCNc1c(C)c(=O)c1=O

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
PRKCA P17252 1/20 0.38
PRKCE Q02156 1/20 0.38
PRKCQ Q04759 1/20 0.38
PRKCD Q05655 1/20 0.38
DNM1 Q05193 1/20 0.38
DGKA P23743 1/20 0.37
MAPT P10636 1/20 0.37
MAPK1 P28482 1/20 0.37
TLR2 O60603 1/20 0.36
PLA2G2A P14555 2/20 0.36
LPAR3 Q9UBY5 3/20 0.35
LPAR1 Q92633 2/20 0.35
ENPP2 Q13822 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21806905 0.94 ALDH1A1 (0.43) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL21807083 0.92 ALDH1A1 (0.42) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL21230937 0.91 ALDH1A1 (0.41) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL22645923 0.91 ALDH1A1 (0.40) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL18641664 0.91 ALDH1A1 (0.40) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL18641797 0.91 DNM1 (0.40) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL21461639 0.91 ALDH1A1 (0.40) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL20500800 0.91 ALDH1A1 (0.40) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL31065316 0.91 ALDH1A1 (0.40) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL31065289 0.91 ALDH1A1 (0.40) ALDH1A1LMNAPRKCAPRKCEPRKCQ

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3458105-B1 POLYNUCLEOTIDES ENCODING GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE FOR THE TREATMENT OF GALACTOSEMIA TYPE 1 MODERNATX INC (US) 2024-01-17 EP disclosed
EP-3718565-B1 RESPIRATORY VIRUS VACCINES MODERNATX INC (US) 2022-04-27 EP disclosed