Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | YAP1 | P46937 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.42 |
| ▸ | WNK1 | Q9H4A3 | 2/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20779747 | 0.87 | KMT2A (0.46) | KMT2AMEN1L3MBTL1YAP1PTGS2 | |
| SCHEMBL20779767 | 0.84 | CYP3A4 (0.47) | KMT2AMEN1L3MBTL1YAP1WNK1 | |
| SCHEMBL15068133 | 0.79 | YAP1 (0.51) | BRD4KMT2AYAP1PTGS2PTGS1 | |
| SCHEMBL19203959 | 0.76 | WNK1 (0.70) | KMT2AMEN1L3MBTL1WNK1ALDH1A1 | |
| SCHEMBL20779592 | 0.74 | L3MBTL1 (0.37) | KMT2AMEN1L3MBTL1YAP1ALOX15 | |
| SCHEMBL11292547 | 0.74 | EPAS1 (0.41) | PTGS2PTGS1ALDH1A1LMNAMAPT | |
| SCHEMBL20779661 | 0.73 | BRD4 (0.46) | BRD4KMT2AMEN1L3MBTL1YAP1 | |
| SCHEMBL20779809 | 0.73 | BRD4 (0.39) | BRD4KMT2AMEN1L3MBTL1ALOX15 | |
| SCHEMBL20779659 | 0.72 | YAP1 (0.56) | BRD4KMT2AMEN1YAP1PTGS2 | |
| SCHEMBL3476117 | 0.71 | KDM4E (0.56) | KMT2AMEN1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11192865-B2 | Benzosulfonyl compounds | VIVACE THERAPEUTICS, INC. (US) | 2021-12-07 | — | — | US | disclosed |
| US-20200354325-A1 | BENZOSULFONYL COMPOUNDS | VIVACE THERAPEUTICS, INC. | 2020-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11192865-B2 | Benzosulfonyl compounds | YAP1, TEAD2, TEAD1 | BRD4 7/4885KMT2A 795/4885MEN1 3954/4885 |
| US-20200354325-A1 | BENZOSULFONYL COMPOUNDS | YAP1, TEAD2, TEAD1 | BRD4 7/4885KMT2A 795/4885MEN1 3954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.