Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 13/20 | 0.62 |
| ▸ | CA12 | O43570 | 2/20 | 0.57 |
| ▸ | RPA1 | P27694 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22415502 | 0.88 | ALPL (0.72) | ALPLMAPTMEN1KMT2ANPC1 | |
| SCHEMBL4198722 | 0.85 | ALPL (0.71) | ALPLCA12CA9MEN1KMT2A | |
| SCHEMBL22415501 | 0.80 | ALPL (0.63) | ALPLCA12RPA1CA9MEN1 | |
| SCHEMBL4384447 | 0.78 | ALPL (0.64) | ALPLCA12RPA1CA9MAPT | |
| SCHEMBL2056464 | 0.77 | MEN1 (0.49) | ALPLMAPTMEN1KMT2ANPC1 | |
| SCHEMBL13539286 | 0.77 | ALPL (1.00) | ALPLCA9MAPTMEN1KMT2A | |
| SCHEMBL14152904 | 0.76 | MAPT (0.77) | ALPLCA12RPA1CA9MAPT | |
| SCHEMBL3435547 | 0.76 | ALPL (0.74) | ALPLCA12CA9MAPTMEN1 | |
| SCHEMBL27951168 | 0.76 | ALPL (0.59) | ALPLCA12RPA1CA9TP53 | |
| SCHEMBL3447352 | 0.73 | ALPL (1.00) | ALPLCA12RPA1CA9TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11332461-B2 | 2-(1H-pyrazol-3-yl) phenol compound and use thereof | BEIJING JIALIN PHARMACEUTICAL INC. (CN) | 2022-05-17 | — | — | US | disclosed |
| US-20200354342-A1 | 2-(1H-PYRAZOL-3-YL) PHENOL COMPOUND AND USE THEREOF | BEIJING JIALIN PHARMACEUTICAL INC. (CN) | 2020-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11332461-B2 | 2-(1H-pyrazol-3-yl) phenol compound and use thereof | VHL, PAH, TP53 | ALPL 862/4885CA12 1481/4885RPA1 3155/4885 |
| US-20200354342-A1 | 2-(1H-PYRAZOL-3-YL) PHENOL COMPOUND AND USE THEREOF | VHL, PAH, TP53 | ALPL 862/4885CA12 1481/4885RPA1 3155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.