Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 4/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11890404 | 0.85 | HTR2A (0.39) | HTR2ASLC6A4KCNH2JAK2MEN1 | |
| SCHEMBL16956920 | 0.82 | HTR2A (0.37) | HTR2ASLC6A4KCNH2JAK2ALK | |
| SCHEMBL29429683 | 0.81 | CYP2D6 (0.49) | HTR2ASLC6A4KCNH2HTR2CALK | |
| SCHEMBL896090 | 0.81 | CYP2D6 (0.49) | HTR2ASLC6A4KCNH2HTR2CALK | |
| SCHEMBL669891 | 0.81 | CYP2D6 (0.49) | HTR2ASLC6A4KCNH2HTR2CALK | |
| SCHEMBL895659 | 0.81 | CYP2D6 (0.49) | HTR2ASLC6A4KCNH2HTR2CALK | |
| SCHEMBL20371087 | 0.81 | MCHR1 (0.39) | HTR2ASLC6A4KCNH2JAK2HTR2C | |
| SCHEMBL18376038 | 0.80 | HTR2A (0.34) | HTR2ASLC6A4KCNH2PDE2AJAK2 | |
| SCHEMBL16830034 | 0.79 | ALOX12 (0.41) | MEN1KMT2AHTTLMNAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL16756389 | 0.78 | ALDH1A1 (0.40) | MEN1KMT2ALMNAL3MBTL1ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240025908-A1 | COMPOUND USED AS KINASE INHIBITOR AND USE THEREOF | TYK MEDICINES, INC. (CN) | 2024-01-25 | — | — | US | disclosed |
| WO-2020224626-A1 | COMPOUND USED AS KINASE INHIBITOR AND APPLICATION THEREOF | 浙江同源康医药股份有限公司 | 2020-11-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240025908-A1 | COMPOUND USED AS KINASE INHIBITOR AND USE THEREOF | ROS1, ALK, RET | HTR2A 4196/4885SLC6A4 2823/4885KCNH2 2741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.