Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16959139 | 0.87 | KCNH2 (0.38) | HTR2ASLC6A4KCNH2MEN1KMT2A | |
| SCHEMBL11890404 | 0.85 | HTR2A (0.39) | HTR2ASLC6A4KCNH2MEN1KMT2A | |
| SCHEMBL22646883 | 0.82 | HTR2A (0.37) | HTR2ASLC6A4KCNH2MEN1KMT2A | |
| SCHEMBL16954278 | 0.82 | ALDH1A1 (0.44) | HTR2ASLC6A4KCNH2MEN1KMT2A | |
| SCHEMBL16952708 | 0.81 | NFE2L2 (0.41) | HTR2ASLC6A4KCNH2MEN1KMT2A | |
| SCHEMBL16951800 | 0.81 | HTT (0.35) | SLC6A4MEN1KMT2AHTTMAPT | |
| SCHEMBL16951864 | 0.81 | KMT2A (0.37) | HTR2ASLC6A4MEN1KMT2AHTT | |
| SCHEMBL16962116 | 0.81 | HTT (0.32) | HTR2ASLC6A4KCNH2HTTLMNA | |
| SCHEMBL16952054 | 0.79 | CYP2D6 (0.46) | HTR2AMEN1KMT2AHTTMAPT | |
| SCHEMBL16962099 | 0.79 | L3MBTL1 (0.41) | HTR2ASLC6A4KCNH2MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |