Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL139251 | 0.87 | POLB (0.55) | POLBGAAGFERHTR6TSHR | |
| SCHEMBL22647158 | 0.85 | GAA (0.47) | GAAHTTFEN1KMT2AMEN1 | |
| SCHEMBL12903976 | 0.85 | HTR6 (0.57) | POLBGAAGFERHTR6TSHR | |
| Sulfuric Acid SCHEMBL8386859 | 0.84 | POLB (0.51) | POLBGAAGFERHTR6TSHR | |
| SCHEMBL9456372 | 0.81 | HTR6 (0.50) | POLBGAAGFERHTR6TSHR | |
| SCHEMBL29709995 | 0.81 | POLB (0.66) | POLBGAAGFERHTR6TSHR | |
| SCHEMBL312517 | 0.81 | POLB (0.66) | POLBGAAGFERHTR6TSHR | |
| SCHEMBL22647161 | 0.78 | CA1 (0.51) | POLBGAAHTR6HTTKMT2A | |
| SCHEMBL28245930 | 0.78 | POLB (0.53) | POLBGAAGFERHTR6TSHR | |
| SCHEMBL10425221 | 0.76 | HSD11B1 (0.53) | POLBGAAGFERHTR6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020227180-A1 | SULFUR AND AMIDE TROPOLONE INHIBITORS OF NUCLEOTIDYL TRANSFERASES AND USES THEREFOR | SAINT LOUIS UNIVERSITY (US) | 2020-11-12 | — | — | WO | disclosed |