Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 1/20 | 0.53 |
| ▸ | ARG2 | P78540 | 1/20 | 0.53 |
| ▸ | FDPS | P14324 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.51 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.51 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.51 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.51 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.51 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.49 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2264734 | 1.00 | ARG1 (0.53) | ARG1ARG2FDPSALDH1A1CYP3A4 | |
| SCHEMBL3510790 | 0.82 | ALDH1A1 (0.59) | ARG1ARG2FDPSALDH1A1CYP3A4 | |
| SCHEMBL5692256 | 0.81 | FDPS (0.54) | ARG1ARG2FDPSALDH1A1CYP3A4 | |
| SCHEMBL20644246 | 0.80 | HRH4 (0.57) | ARG1ARG2FDPSALDH1A1CYP3A4 | |
| SCHEMBL11611208 | 0.78 | ARG1 (0.51) | ARG1ARG2FDPSALDH1A1CYP3A4 | |
| SCHEMBL11154182 | 0.78 | ARG1 (0.61) | ARG1ARG2FDPSALDH1A1CYP3A4 | |
| SCHEMBL11159616 | 0.78 | ARG1 (0.61) | ARG1ARG2FDPSALDH1A1CYP3A4 | |
| SCHEMBL11615111 | 0.76 | ARG1 (0.50) | ARG1ARG2FDPSALDH1A1CYP3A4 | |
| SCHEMBL11169995 | 0.76 | HRH4 (0.50) | ARG1ARG2FDPSALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL11626458 | 0.75 | ARG1 (0.49) | ARG1ARG2FDPSALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445440-B2 | Dimeric IAP inhibitors | NOVARTIS AG (CH) | 2013-05-21 | — | — | US | disclosed |
| US-20110206690-A1 | DIMERIC IAP INHIBITORS | NOVARTIS AG (CH) | 2011-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110206690-A1 | DIMERIC IAP INHIBITORS | XIAP, BIRC5, BIRC2 | ARG1 3683/4885ARG2 3473/4885FDPS 3123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.