Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29405787 | 1.00 | ATM (0.50) | ATMCYP2C9CYP2C19ALDH1A1THRB | |
| SCHEMBL22647454 | 1.00 | ATM (0.50) | ATMCYP2C9CYP2C19ALDH1A1THRB | |
| SCHEMBL22649244 | 0.89 | HCRTR1 (0.48) | ATMALDH1A1POLB | |
| SCHEMBL22651913 | 0.89 | L3MBTL1 (0.41) | ATMCYP2C9CYP2C19ALDH1A1THRB | |
| SCHEMBL22651774 | 0.89 | PSEN1 (0.48) | — | |
| SCHEMBL22634064 | 0.88 | PTPN1 (0.50) | ALDH1A1HSD17B10L3MBTL1POLBGAA | |
| SCHEMBL22634065 | 0.88 | PTPN1 (0.50) | ALDH1A1HSD17B10L3MBTL1POLBGAA | |
| SCHEMBL22647530 | 0.86 | TSHR (0.48) | CYP2C19ALDH1A1L3MBTL1GAACYP3A4 | |
| SCHEMBL22649659 | 0.86 | CYP3A4 (0.42) | ATMCYP2C9CYP2C19ALDH1A1L3MBTL1 | |
| SCHEMBL22647529 | 0.86 | TSHR (0.48) | CYP2C19ALDH1A1L3MBTL1GAACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200354318-A1 | THIOSEMICARBAZATES AND USES THEREOF | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2020-11-12 | — | — | US | disclosed |
| WO-2020227594-A1 | COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2020-11-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200354318-A1 | THIOSEMICARBAZATES AND USES THEREOF | TST, ABAT, AADAC | ATM 3180/4885CYP2C9 1573/4885CYP2C19 1439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.