Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ACE | P12821 | 2/20 | 0.42 |
| ▸ | CPA1 | P15085 | 2/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22634065 | 1.00 | PTPN1 (0.50) | PTPN1ALDH1A1GAAMMENPSR1 | |
| SCHEMBL22634046 | 0.89 | GAA (0.45) | PTPN1ALDH1A1GAAMMEHSD17B10 | |
| SCHEMBL22634044 | 0.89 | GAA (0.45) | PTPN1ALDH1A1GAAMMEHSD17B10 | |
| SCHEMBL22647454 | 0.88 | ATM (0.50) | ALDH1A1GAAHSD17B10L3MBTL1POLB | |
| SCHEMBL22647465 | 0.88 | ATM (0.50) | ALDH1A1GAAHSD17B10L3MBTL1POLB | |
| SCHEMBL29405787 | 0.88 | ATM (0.50) | ALDH1A1GAAHSD17B10L3MBTL1POLB | |
| SCHEMBL22634274 | 0.88 | ALDH1A1 (0.48) | PTPN1ALDH1A1GAAMMEL3MBTL1 | |
| SCHEMBL22634276 | 0.88 | ALDH1A1 (0.48) | PTPN1ALDH1A1GAAMMEL3MBTL1 | |
| SCHEMBL22634043 | 0.87 | MME (0.47) | GAAMME | |
| SCHEMBL22634220 | 0.87 | MME (0.47) | GAAMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10919882-B2 | Compounds for use in synthesis of peptidomimetics | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2021-02-16 | — | — | US | disclosed |
| US-20200354318-A1 | THIOSEMICARBAZATES AND USES THEREOF | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2020-11-12 | — | — | US | disclosed |
| WO-2020227594-A1 | COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2020-11-12 | — | — | WO | disclosed |
| WO-2020227592-A1 | THIOSEMICARBAZATES AND USES THEREOF | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2020-11-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10919882-B2 | Compounds for use in synthesis of peptidomimetics | DNPEP, NPEPPS, PAM | PTPN1 2822/4885ALDH1A1 4622/4885GAA 2546/4885 |
| US-20200354318-A1 | THIOSEMICARBAZATES AND USES THEREOF | TST, ABAT, AADAC | PTPN1 2995/4885ALDH1A1 981/4885GAA 1001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.