Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 1/20 | 0.46 |
| ▸ | TFPI | P10646 | 1/20 | 0.45 |
| ▸ | NMT1 | P30419 | 5/20 | 0.45 |
| ▸ | NMT2 | O60551 | 4/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22640903 | 1.00 | TLR2 (0.46) | TLR2TFPINMT1NMT2GRIN2D | |
| SCHEMBL29673329 | 0.89 | KEAP1 (0.48) | TLR2TFPIGRIN2DGRIN3BGRIN1 | |
| SCHEMBL24616813 | 0.86 | GRIN2D (0.49) | TLR2TFPINMT1NMT2GRIN2D | |
| SCHEMBL22648216 | 0.86 | GRIN2D (0.49) | TLR2TFPINMT1NMT2GRIN2D | |
| SCHEMBL22648206 | 0.85 | KEAP1 (0.47) | TFPIGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL24616812 | 0.85 | GRIN2D (0.49) | TLR2TFPINMT1NMT2GRIN2D | |
| SCHEMBL29517692 | 0.83 | KEAP1 (0.44) | KEAP1SIRT5FOLH1 | |
| SCHEMBL29673327 | 0.83 | GNPAT (0.46) | KEAP1SIRT5FOLH1 | |
| SCHEMBL6856783 | 0.81 | NMT2 (0.46) | TLR2TFPINMT1NMT2GRIN2D | |
| SCHEMBL6856774 | 0.81 | NMT2 (0.46) | TLR2TFPINMT1NMT2GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020225245-A1 | VASCULAR CHOLESTEROL INHIBITORS AND USE THEREOF | IPROTEOS, S.L. (ES) | 2020-11-12 | — | — | WO | disclosed |