SCHEMBL22648282

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL39430	0.86	TDP1 (0.72)	TDP1ALDH1A1L3MBTL1CYP3A4ALOX15
	SCHEMBL18559184	0.82	MAPT (0.50)	TDP1ALDH1A1L3MBTL1CYP3A4ALOX15
	SCHEMBL22648059	0.81	TDP1 (0.54)	TDP1ALDH1A1L3MBTL1CYP3A4ALOX15
	SCHEMBL22427774	0.80	MEN1 (0.47)	TDP1ALDH1A1L3MBTL1CYP3A4ALOX15
	SCHEMBL22648062	0.79	TDP1 (0.56)	TDP1ALDH1A1L3MBTL1CYP3A4ALOX15
	SCHEMBL18268224	0.79	TDP1 (0.56)	TDP1ALDH1A1L3MBTL1CYP3A4ALOX15
	SCHEMBL790636	0.79	TDP1 (0.64)	TDP1ALDH1A1L3MBTL1CYP3A4ALOX15
	SCHEMBL9934007	0.78	TDP1 (0.81)	TDP1ALDH1A1L3MBTL1CYP3A4ALOX15
	SCHEMBL20131116	0.77	ALDH1A1 (0.56)	TDP1ALDH1A1L3MBTL1THRBRECQL
	SCHEMBL7213755	0.76	TDP1 (0.59)	TDP1ALDH1A1L3MBTL1CYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.