Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.81 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.81 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.81 |
| ▸ | TSHR | P16473 | 4/20 | 0.81 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.81 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.81 |
| ▸ | THRB | P10828 | 3/20 | 0.81 |
| ▸ | RECQL | P46063 | 3/20 | 0.81 |
| ▸ | LMNA | P02545 | 1/20 | 0.81 |
| ▸ | ATM | Q13315 | 1/20 | 0.81 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KCNH3 | Q9ULD8 | 7/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL39430 | 0.91 | TDP1 (0.72) | TDP1ALDH1A1HSD17B10L3MBTL1ALOX15 | |
| SCHEMBL675141 | 0.90 | TDP1 (0.68) | TDP1ALDH1A1HSD17B10L3MBTL1ALOX15 | |
| SCHEMBL38820 | 0.90 | ALDH1A1 (1.00) | TDP1ALDH1A1HSD17B10L3MBTL1ALOX15 | |
| SCHEMBL16961901 | 0.88 | ALDH1A1 (0.65) | TDP1ALDH1A1HSD17B10L3MBTL1ALOX15 | |
| SCHEMBL21480372 | 0.88 | L3MBTL1 (0.65) | TDP1ALDH1A1HSD17B10L3MBTL1ALOX15 | |
| N,N'-Diphenyl-P-Phenylenediamine SCHEMBL10454791 | 0.88 | ALDH1A1 (0.95) | TDP1ALDH1A1HSD17B10L3MBTL1ALOX15 | |
| N,N'-Diphenyl-P-Phenylenediamine SCHEMBL10454790 | 0.88 | ALDH1A1 (0.95) | TDP1ALDH1A1HSD17B10L3MBTL1ALOX15 | |
| SCHEMBL8467092 | 0.88 | ALDH1A1 (0.95) | TDP1ALDH1A1HSD17B10L3MBTL1ALOX15 | |
| SCHEMBL11659836 | 0.88 | ALDH1A1 (0.65) | TDP1ALDH1A1HSD17B10L3MBTL1ALOX15 | |
| Hydrogen Sulfide SCHEMBL8467082 | 0.88 | ALDH1A1 (0.95) | TDP1ALDH1A1HSD17B10L3MBTL1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4752119-A | Electrochromic display devices | NEC CORPORATION (JP) | 1988-06-21 | — | — | US | claimed |
| WO-2024137665-A2 | RUBBER COMPOSITIONS COMPRISING ANTIDEGRADANTS | FLEXSYS AMERICA L.P. (US) | 2024-06-27 | — | — | WO | disclosed |
| WO-2023215590-A2 | ANTIDEGRADANT COMPOUNDS AND USES THEREOF | FLEXSYS AMERICA L.P. (US) | 2023-11-09 | — | — | WO | disclosed |
| US-8835687-B2 | Method for preparation of 4,4′-dinitrodiphenylamine and 4,4′-bis(alkylamino)diphenylamine with the base catalyst complex | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2014-09-16 | — | — | US | disclosed |
| US-8759587-B2 | Method for preparation of 4,4′-dinitrodiphenylamine and 4,4′-bis(alkylamino)diphenylamine by using 4-nitroaniline | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2014-06-24 | — | — | US | disclosed |
| US-20120197044-A1 | PRODUCTION METHOD FOR 4,4'-BIS(ALKYLAMINO) DIPHENYLAMINE | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2012-08-02 | — | — | US | disclosed |
| US-20120157713-A1 | METHOD FOR PREPARATION OF 4,4'-DINITRODIPHENYLAMINE AND 4,4'-BIS(ALKYLAMINO)DIPHENYLAMINE WITH THE BASE CATALYST COMPLEX | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2012-06-21 | — | — | US | disclosed |
| US-20120157714-A1 | METHOD FOR PREPARATION OF 4,4'-DINITRODIPHENYLAMINE AND 4,4'-BIS(ALKYLAMINO)DIPHENYLAMINE BY USING 4-NITROANILINE | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2012-06-21 | — | — | US | disclosed |
| US-4752119-A | Electrochromic display devices | NEC CORPORATION (JP) | 1988-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157714-A1 | METHOD FOR PREPARATION OF 4,4'-DINITRODIPHENYLAMINE AND 4,4'-BIS(ALKYLAMINO)DIPHENYLAMINE BY USING 4-NITROANILINE | NAAA, AADAT, HPD | TDP1 3294/4885ALDH1A1 429/4885HSD17B10 403/4885 |
| US-20120157713-A1 | METHOD FOR PREPARATION OF 4,4'-DINITRODIPHENYLAMINE AND 4,4'-BIS(ALKYLAMINO)DIPHENYLAMINE WITH THE BASE CATALYST COMPLEX | NAAA, HNF4A, ABAT | TDP1 2632/4885ALDH1A1 845/4885HSD17B10 335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.