Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 3/20 | 0.45 |
| ▸ | JAK1 | P23458 | 3/20 | 0.45 |
| ▸ | TYK2 | P29597 | 3/20 | 0.45 |
| ▸ | JAK3 | P52333 | 3/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.42 |
| ▸ | IDO1 | P14902 | 6/20 | 0.41 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL22635786 | 0.99 | JAK2 (0.44) | JAK2JAK1TYK2JAK3CHEK2 | |
| SCHEMBL21061140 | 0.81 | IDO1 (0.50) | IDO1CHRNA1CYP2C8CYP2C9CYP2C19 | |
| SCHEMBL21138139 | 0.77 | IDO1 (0.52) | IDO1CYP2C8CYP2C9TDO2 | |
| SCHEMBL7964040 | 0.77 | IDO1 (0.56) | IDO1CHRNA1CYP2C8CYP2C9CYP2C19 | |
| SCHEMBL19297195 | 0.76 | HTR1D (0.45) | JAK2JAK1TYK2JAK3CHEK2 | |
| SCHEMBL30735531 | 0.76 | HTR1D (0.45) | JAK2JAK1TYK2JAK3CHEK2 | |
| SCHEMBL21138146 | 0.76 | GPR119 (0.51) | JAK2JAK1TYK2JAK3CHEK2 | |
| SCHEMBL29050696 | 0.75 | JAK2 (0.44) | JAK2JAK1TYK2JAK3CHEK2 | |
| SCHEMBL21138142 | 0.75 | IDO1 (0.52) | IDO1CHRNA1CYP2C19TDO2IRAK4 | |
| SCHEMBL21138046 | 0.74 | IDO1 (0.41) | IDO1CHRNA1CYP2C8CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200352931-A1 | OXALAMIDES AS MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE | Phenex Discovery Verwaltungs-GmbH (DE) | 2020-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200352931-A1 | OXALAMIDES AS MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE | IDO1, IDO2, INMT | JAK2 1350/4885JAK1 1543/4885TYK2 1279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.