Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 3/20 | 0.44 |
| ▸ | JAK1 | P23458 | 3/20 | 0.44 |
| ▸ | TYK2 | P29597 | 3/20 | 0.44 |
| ▸ | JAK3 | P52333 | 3/20 | 0.44 |
| ▸ | CDC7 | O00311 | 1/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | KDM4B | O94953 | 1/20 | 0.41 |
| ▸ | KDM5C | P41229 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.41 |
| ▸ | PRKD1 | Q15139 | 6/20 | 0.40 |
| ▸ | PRKD2 | Q9BZL6 | 6/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6118725 | 0.91 | PRKD1 (0.45) | JAK2JAK1TYK2JAK3CDC7 | |
| SCHEMBL4173650 | 0.89 | PROKR1 (0.48) | DDB1CRBNKDM4BKDM5CKDM5B | |
| SCHEMBL1846196 | 0.77 | SLC6A2 (0.40) | JAK2JAK1TYK2JAK3CDC7 | |
| SCHEMBL13490541 | 0.77 | NNMT (0.46) | JAK2JAK1TYK2JAK3CDC7 | |
| Trifluoroacetic Acid SCHEMBL20641568 | 0.76 | KDM5C (0.39) | DDB1CRBNKDM4BKDM5CKDM5B | |
| SCHEMBL1035168 | 0.76 | NPY5R (0.41) | JAK2JAK1TYK2JAK3DDB1 | |
| Hydrochloric Acid SCHEMBL20969010 | 0.76 | NNMT (0.45) | JAK2JAK1TYK2JAK3CDC7 | |
| SCHEMBL13858261 | 0.76 | HRH4 (0.49) | MKNK1MKNK2HRH4 | |
| SCHEMBL31196421 | 0.75 | AKR1C3 (0.45) | DDB1CRBNKDM4BKDM5CKDM5B | |
| SCHEMBL31196453 | 0.75 | AKR1C3 (0.45) | DDB1CRBNKDM4BKDM5CKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116589452-A | Myricetin derivative containing piperidine amide, preparation method and application | 贵州大学 | 2023-08-15 | — | — | CN | disclosed |