Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | BMX | P51813 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16066373 | 0.95 | KDM4E (0.48) | KDM4EHPGDALDH1A1MAPTLMNA | |
| SCHEMBL16066129 | 0.93 | KDM4E (0.46) | KDM4EHPGDALDH1A1MAPTLMNA | |
| SCHEMBL16066409 | 0.89 | KDM4E (0.44) | KDM4EHPGDALDH1A1MAPTLMNA | |
| SCHEMBL22649045 | 0.87 | KDM4E (0.52) | KDM4EHPGDALDH1A1MAPTLMNA | |
| SCHEMBL16066176 | 0.86 | ALDH1A1 (0.51) | KDM4EHPGDALDH1A1MAPTLMNA | |
| SCHEMBL16066939 | 0.86 | KDM4E (0.44) | KDM4EHPGDALDH1A1MAPTLMNA | |
| SCHEMBL15128408 | 0.85 | MEN1 (0.44) | KDM4EHPGDALDH1A1MAPTLMNA | |
| SCHEMBL18851864 | 0.85 | HPGD (0.50) | KDM4EHPGDALDH1A1MAPTLMNA | |
| SCHEMBL16066607 | 0.85 | KDM4E (0.45) | KDM4EHPGDALDH1A1MAPTLMNA | |
| SCHEMBL16066375 | 0.85 | HPGD (0.45) | KDM4EHPGDALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200358005-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200358005-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | PIEZO1, L1CAM, EFNA1 | KDM4E 2430/4885HPGD 1383/4885ALDH1A1 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.