Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16067191 | 0.96 | KDM4E (0.36) | KDM4EATML3MBTL1PLA2G10KMT2A | |
| SCHEMBL16067212 | 0.94 | KDM4E (0.34) | KDM4EATML3MBTL1PLA2G10KMT2A | |
| SCHEMBL16067132 | 0.92 | PDE10A (0.34) | KDM4EATML3MBTL1PLA2G10KMT2A | |
| SCHEMBL16067174 | 0.89 | KMT2A (0.36) | KDM4EATML3MBTL1PLA2G10KMT2A | |
| SCHEMBL22649070 | 0.88 | ATM (0.33) | KDM4EATML3MBTL1KMT2AMEN1 | |
| SCHEMBL16067215 | 0.87 | KDM4E (0.34) | KDM4EATML3MBTL1PLA2G10KMT2A | |
| SCHEMBL19652297 | 0.87 | L3MBTL1 (0.44) | KDM4EATML3MBTL1PLA2G10KMT2A | |
| SCHEMBL17033601 | 0.87 | KDM4E (0.36) | KDM4EATML3MBTL1PLA2G10KMT2A | |
| SCHEMBL16067205 | 0.86 | ATM (0.39) | KDM4EATML3MBTL1PLA2G10KMT2A | |
| SCHEMBL16066772 | 0.86 | KDM4E (0.33) | KDM4EATML3MBTL1PLA2G10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200358005-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200358005-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | PIEZO1, L1CAM, EFNA1 | KDM4E 2430/4885ATM 3991/4885L3MBTL1 2124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.