Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29345448 | 0.61 | ALDH1A1 (0.34) | — | |
| SCHEMBL18623692 | 0.58 | GABRR1 (0.35) | — | |
| SCHEMBL10808532 | 0.57 | PTPN1 (0.35) | — | |
| SCHEMBL18266434 | 0.55 | — | — | |
| SCHEMBL25709006 | 0.54 | GABRP (0.33) | NOTUM | |
| SCHEMBL16181677 | 0.54 | KDM4E (0.30) | — | |
| SCHEMBL8472068 | 0.54 | ALDH1A1 (0.38) | — | |
| SCHEMBL21166245 | 0.53 | NOTUM (0.36) | NOTUM | |
| SCHEMBL19122022 | 0.51 | TPMT (0.30) | — | |
| SCHEMBL422352 | 0.51 | RXRA (0.51) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020227101-A1 | KCNT1 INHIBITORS AND METHODS OF USE | PRAXIS PRECISION MEDICINES, INC. (US) | 2020-11-12 | — | — | WO | disclosed |