Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15436603 | 0.86 | TDP1 (0.40) | CYP2C9CYP2C19TDP1HTR2AHRH1 | |
| SCHEMBL30792552 | 0.82 | HTR2A (0.33) | CYP2C9CYP2C19TDP1HTR2AHRH1 | |
| SCHEMBL23846218 | 0.79 | HTR2A (0.34) | TDP1HTR2AHRH1 | |
| SCHEMBL1601192 | 0.77 | — | — | |
| SCHEMBL11690029 | 0.77 | DNM1 (0.36) | TDP1HTR2AHRH1 | |
| SCHEMBL30761776 | 0.77 | ALDH1A1 (0.43) | TDP1HTR2AHRH1 | |
| SCHEMBL571022 | 0.77 | CHRM2 (0.35) | TDP1HTR2AHRH1 | |
| SCHEMBL5581501 | 0.76 | ENPEP (0.36) | — | |
| SCHEMBL7684766 | 0.76 | — | — | |
| SCHEMBL2454883 | 0.75 | MAPT (0.46) | HTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8785511-B2 | Silicone-containing polyurethane foam | WACKER CHEMIE AG (DE) | 2014-07-22 | — | — | US | disclosed |
| US-20130253085-A1 | SILICONE-CONTAINING POLYURETHANE FOAM | WACKER CHEMIE AG (DE) | 2013-09-26 | — | — | US | disclosed |
| US-8450384-B2 | Polyurethane foam containing silicone | WACKER CHEMIE AG (DE) | 2013-05-28 | — | — | US | disclosed |
| EP-2158247-B1 | POLYURETHANE FOAM CONTAINING SILICON | WACKER CHEMIE AG (DE) | 2013-03-13 | — | — | EP | disclosed |
| US-20130005847-A1 | POLYURETHANE FOAM CONTAINING SILICONE | WACKER CHEMIE AG (DE) | 2013-01-03 | — | — | US | disclosed |
| US-8329770-B2 | Silicon-containing foams | WACKER CHEMIE AG (DE) | 2012-12-11 | — | — | US | disclosed |
| US-20110201712-A1 | POLYURETHANE FOAM CONTAINING SILICONE | WACKER CHEMIE AG (DE) | 2011-08-18 | — | — | US | disclosed |
| US-20100305229-A1 | SILICON-CONTAINING FOAMS | WACKER CHEMIE AG (DE) | 2010-12-02 | — | — | US | disclosed |
| US-20100305226-A1 | POLYURETHANE FOAM CONTAINING SILICONE | WACKER CHEMIE AG (DE) | 2010-12-02 | — | — | US | disclosed |
| US-20090105358-A1 | SILICONE-CONTAINING FOAMS | WACKER CHEMIE AG (DE) | 2009-04-23 | — | — | US | disclosed |
| EP-1485419-B1 | FOAMS CONTAINING SILICON | CONSORTIUM ELEKTROCHEM IND (DE) | 2005-06-15 | — | — | EP | disclosed |