Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22645832 | 0.95 | GPR84 (0.33) | ALDH1A1MAPTADAMTS5 | |
| SCHEMBL21842842 | 0.90 | KDM4E (0.31) | KDM4EGAA | |
| SCHEMBL21842648 | 0.87 | ALDH1A1 (0.35) | ALDH1A1MAPTKDM4EGAAMEN1 | |
| SCHEMBL22649778 | 0.87 | ALDH1A1 (0.36) | ALDH1A1MAPTKDM4EGAAMEN1 | |
| SCHEMBL22645965 | 0.85 | ALDH1A1 (0.35) | ALDH1A1MAPTKDM4EGAAMEN1 | |
| SCHEMBL21473487 | 0.85 | — | — | |
| SCHEMBL21842762 | 0.85 | ALDH1A1 (0.40) | ALDH1A1MAPTKDM4EGAAMEN1 | |
| SCHEMBL22646017 | 0.85 | SMN1; SMN2 (0.35) | ALDH1A1MAPTL3MBTL1TDP1SMN1; SMN2 | |
| SCHEMBL23733306 | 0.84 | — | — | |
| SCHEMBL21842839 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155267-A2 | MRNAS ENCODING METABOLIC REPROGRAMMING POLYPEPTIDES AND USES THEREOF | MODERNATX, INC. (US) | 2021-08-05 | — | — | WO | disclosed |
| WO-2020227510-A1 | POLYNUCLEOTIDES FOR DISRUPTING IMMUNE CELL ACTIVITY AND METHODS OF USE THEREOF | MODERNATX, INC. (US) | 2020-11-12 | — | — | WO | disclosed |