Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21231196 | 0.95 | MMP3 (0.34) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL24807494 | 0.93 | MMP3 (0.36) | — | |
| SCHEMBL21842747 | 0.89 | — | — | |
| SCHEMBL22649779 | 0.85 | ALDH1A1 (0.35) | SMN1; SMN2ALDH1A1MAPTTDP1L3MBTL1 | |
| SCHEMBL21842648 | 0.85 | ALDH1A1 (0.35) | SMN1; SMN2ALDH1A1MAPTTDP1L3MBTL1 | |
| SCHEMBL23268308 | 0.84 | SMN1; SMN2 (0.36) | SMN1; SMN2ALDH1A1MAPTTDP1L3MBTL1 | |
| SCHEMBL21472625 | 0.83 | — | — | |
| SCHEMBL21472779 | 0.82 | — | — | |
| SCHEMBL22645832 | 0.80 | GPR84 (0.33) | ALDH1A1MAPT | |
| SCHEMBL21230881 | 0.80 | GPR84 (0.33) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021076805-A1 | MRNAS ENCODING IMMUNE MODULATING POLYPEPTIDES AND USES THEREOF | Moderna TX, Inc. (US) | 2021-04-22 | — | — | WO | disclosed |
| WO-2020227537-A1 | DIFFERENTIALLY EXPRESSED IMMUNE CELL MICRORNAS FOR REGULATION OF PROTEIN EXPRESSION | Modernatx, Inc (US) | 2020-11-12 | — | — | WO | disclosed |