SCHEMBL22650220

SCHEMBL22650220

Cn1nccc1/N=N/c1sc(N)nc1-c1cccnc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.58
MAPT P10636 5/20 0.58
KMT2A Q03164 5/20 0.58
TDP1 Q9NUW8 4/20 0.58
ALDH1A1 P00352 3/20 0.58
MAPK1 P28482 4/20 0.42
LMNA P02545 3/20 0.42
MMP14 P50281 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
RECQL P46063 2/20 0.42
HTT P42858 1/20 0.42
GBA1 P04062 1/20 0.42
HPGD P15428 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
TGFBR1 P36897 1/20 0.41
PIK3CD O00329 2/20 0.39
PIK3CA P42336 2/20 0.39
PI4KA P42356 2/20 0.39
PI4KB Q9UBF8 2/20 0.39
PIP5K1C O60331 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22650267 0.88 MAPT (0.56) MEN1MAPTKMT2ATDP1ALDH1A1
SCHEMBL22650233 0.77 MEN1 (0.48) MEN1MAPTKMT2ATDP1ALDH1A1
SCHEMBL22650273 0.77 MAPT (0.51) MEN1MAPTKMT2ATDP1ALDH1A1
SCHEMBL22650271 0.74 MAPT (0.37) MEN1MAPTKMT2ATDP1ALDH1A1
SCHEMBL9833618 0.70 SMN1; SMN2 (0.51) MEN1MAPTKMT2ATDP1ALDH1A1
SCHEMBL9727980 0.68 TGFBR1 (0.51) MEN1MAPTKMT2ATDP1ALDH1A1
SCHEMBL6545502 0.67 ALDH1A1 (0.72) MEN1MAPTKMT2ATDP1ALDH1A1
SCHEMBL1850222 0.65 ADORA2A (0.54) MEN1MAPTKMT2ATDP1ALDH1A1
SCHEMBL13537099 0.64 CYP2A6 (0.58) MAPTALDH1A1LMNAHTTHPGD
SCHEMBL30268376 0.64 CYP2A6 (0.58) MAPTALDH1A1LMNAHTTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3747956-A1 STAINING COMPOSITION, STAINED ARTICLE, AND AZO DYE FUJIFILM Corporation (JP) 2020-12-09 EP disclosed
US-20200354576-A1 DYEING COMPOSITION, DYED PRODUCT, AND AZO COLORING AGENT FUJIFILM CORPORATION (JP) 2020-11-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200354576-A1 DYEING COMPOSITION, DYED PRODUCT, AND AZO COLORING AGENT CYP1B1, CYP1A1, NAT1 MEN1 20/4885MAPT 2728/4885KMT2A 1097/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.