Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PTPRC | P08575 | 1/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PTPRA | P18433 | 1/20 | 0.45 |
| ▸ | PTPRB | P23467 | 1/20 | 0.45 |
| ▸ | PTPRE | P23469 | 1/20 | 0.45 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | AHR | P35869 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6046819 | 0.87 | KMT2A (0.53) | HTTKMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL16651569 | 0.87 | KMT2A (0.53) | HTTKMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL4604248 | 0.84 | CA12 (0.57) | HTTKMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL6012277 | 0.84 | ALDH1A1 (0.51) | HTTKMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL4605157 | 0.83 | L3MBTL1 (0.55) | HTTKMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL1186093 | 0.83 | MAPT (0.51) | KMT2AALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL4605989 | 0.82 | GAA (0.51) | HTTKMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL4604562 | 0.82 | ALDH1A1 (0.60) | HTTKMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL29441245 | 0.82 | ALDH1A1 (0.60) | HTTKMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL16662129 | 0.81 | HTT (0.43) | HTTKMT2AALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020225330-A1 | DHODH INHIBITORS AND THEIR USE AS ANTIVIRAL AGENTS | UNIVERSITÄT HAMBURG (DE) | 2020-11-12 | — | — | WO | disclosed |