Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 4/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.38 |
| ▸ | MERTK | Q12866 | 1/20 | 0.38 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22650374 | 0.92 | ACHE (0.45) | ACHECHEK1LTA4HSSTR5GABRP | |
| SCHEMBL14896982 | 0.80 | HRH3 (0.48) | LTA4HSSTR5GABRPGABRDGABRA1 | |
| SCHEMBL465824 | 0.80 | HRH3 (0.48) | LTA4HSSTR5GABRPGABRDGABRA1 | |
| SCHEMBL465702 | 0.80 | HRH3 (0.48) | LTA4HSSTR5GABRPGABRDGABRA1 | |
| SCHEMBL1126096 | 0.79 | ALDH1A1 (0.47) | LTA4HSSTR5KMT2A | |
| SCHEMBL1126098 | 0.79 | ALDH1A1 (0.47) | LTA4HSSTR5KMT2A | |
| SCHEMBL1126239 | 0.79 | ALDH1A1 (0.47) | LTA4HSSTR5KMT2A | |
| SCHEMBL18291465 | 0.77 | HRH3 (0.46) | ACHECHEK1LTA4HSSTR5GABRP | |
| SCHEMBL13768892 | 0.76 | ALDH1A1 (0.50) | ACHELTA4HSSTR5GABRPGABRD | |
| SCHEMBL2231495 | 0.76 | HRH3 (0.58) | ACHELTA4HSSTR5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |