Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 3/20 | 0.45 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 2/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.36 |
| ▸ | GABRE | P78334 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22650378 | 0.92 | L3MBTL3 (0.40) | ACHECHEK1LTA4HSSTR5KMT2A | |
| SCHEMBL18291465 | 0.82 | HRH3 (0.46) | ACHECHEK1LTA4HSSTR5KMT2A | |
| SCHEMBL2231495 | 0.81 | HRH3 (0.58) | ACHELTA4HSSTR5KMT2AHRH3 | |
| SCHEMBL13768892 | 0.81 | ALDH1A1 (0.50) | ACHELTA4HSSTR5KMT2AHRH3 | |
| SCHEMBL1587073 | 0.80 | ALDH1A1 (0.56) | ACHECHEK1LTA4HJAK2JAK1 | |
| SCHEMBL19231861 | 0.80 | ALDH1A1 (0.46) | KMT2AHRH3MEN1 | |
| SCHEMBL20203525 | 0.80 | ACHE (0.43) | ACHECHEK1LTA4HJAK2JAK1 | |
| SCHEMBL20037557 | 0.79 | LTA4H (0.42) | LTA4HSSTR5KMT2AHRH3GABRP | |
| SCHEMBL18291525 | 0.78 | HRH3 (0.48) | ACHELTA4HSSTR5KMT2AHRH3 | |
| SCHEMBL1035345 | 0.78 | ALDH1A1 (0.56) | HRH3GABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |