Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.30 |
| ▸ | CCND1 | P24385 | 1/20 | 0.30 |
| ▸ | CCND3 | P30281 | 1/20 | 0.30 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22650388 | 0.85 | MAPK8 (0.32) | — | |
| SCHEMBL22650740 | 0.79 | RPS6KA5 (0.32) | SMN1; SMN2 | |
| SCHEMBL19966497 | 0.72 | CDK4 (0.38) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL24619604 | 0.71 | CDK4 (0.31) | CDK4CCND3CDK6 | |
| SCHEMBL29684460 | 0.71 | CDK4 (0.31) | CDK4CCND3CDK6 | |
| SCHEMBL19966537 | 0.71 | CDK4 (0.35) | SMN1; SMN2CDK4CCND1CCND3CDK6 | |
| SCHEMBL2514899 | 0.70 | CDK4 (0.55) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL29669654 | 0.70 | CDK4 (0.55) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL19966561 | 0.68 | KMO (0.38) | SMN1; SMN2CDK4 | |
| SCHEMBL24632941 | 0.68 | CDK4 (0.43) | SMN1; SMN2CDK4CCND1CCND3CDK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |