Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 2/20 | 0.32 |
| ▸ | GSK3B | P49841 | 2/20 | 0.32 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22650387 | 0.85 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL22650740 | 0.76 | RPS6KA5 (0.32) | MAPK8GSK3BCAMKK2PIK3CG | |
| SCHEMBL19966537 | 0.71 | CDK4 (0.35) | MAPK8GSK3BCAMKK2PIK3CG | |
| SCHEMBL24391815 | 0.70 | PDE4B (0.32) | PDE4B | |
| SCHEMBL24970292 | 0.67 | ALDH1A1 (0.45) | PIK3CGALDH1A1GAA | |
| SCHEMBL24619604 | 0.66 | CDK4 (0.31) | — | |
| SCHEMBL24632941 | 0.66 | CDK4 (0.43) | — | |
| SCHEMBL19966561 | 0.66 | KMO (0.38) | PIK3CG | |
| SCHEMBL19966494 | 0.66 | CDK4 (0.47) | GSK3B | |
| SCHEMBL29684460 | 0.66 | CDK4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |