Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 3/20 | 0.31 |
| ▸ | CDK2 | P24941 | 3/20 | 0.31 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.30 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.30 |
| ▸ | CCND3 | P30281 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29684460 | 1.00 | CDK4 (0.31) | CDK4CDK2CDK6TRPV1CDK1 | |
| SCHEMBL24619122 | 0.90 | CDK4 (0.31) | CDK4CDK2CDK6CDK1CCNB1 | |
| SCHEMBL29684659 | 0.90 | GRM2 (0.31) | CDK4CDK2CDK6 | |
| SCHEMBL29727074 | 0.85 | P2RX3 (0.39) | — | |
| SCHEMBL30629591 | 0.83 | CAMKK2 (0.35) | CDK4CDK2CDK6TRPV1CDK1 | |
| SCHEMBL24619105 | 0.82 | CCND3 (0.36) | CDK4CDK6CCND3 | |
| SCHEMBL29684554 | 0.80 | CDK4 (0.33) | CDK4CDK6CCND3 | |
| SCHEMBL24619618 | 0.79 | MAPK1 (0.32) | CDK4CDK6CCND3 | |
| SCHEMBL24619133 | 0.79 | TNF (0.33) | CDK4CDK6CCND3 | |
| SCHEMBL24619226 | 0.79 | CYP11B2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022149057-A1 | CDK INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2022-07-14 | — | — | WO | disclosed |