Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 2/20 | 0.36 |
| ▸ | JAK1 | P23458 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CCND1 | P24385 | 1/20 | 0.30 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29491148 | 1.00 | CCNT1 (0.39) | CCNT1CDK9JAK2JAK1L3MBTL1 | |
| SCHEMBL22650393 | 0.85 | CCNT1 (0.36) | CCNT1CDK9JAK2JAK1KDM4E | |
| SCHEMBL29491154 | 0.85 | CCNT1 (0.36) | CCNT1CDK9JAK2JAK1KDM4E | |
| SCHEMBL22650391 | 0.70 | JAK2 (0.32) | JAK2JAK1 | |
| SCHEMBL24401874 | 0.69 | KDM4E (0.39) | KDM4EALDH1A1MAPT | |
| SCHEMBL22650399 | 0.67 | CDK4 (0.33) | JAK2JAK1ALDH1A1CCND1CDK2 | |
| SCHEMBL22650745 | 0.64 | DCTPP1 (0.35) | — | |
| SCHEMBL29491153 | 0.64 | DCTPP1 (0.35) | — | |
| SCHEMBL24401870 | 0.62 | TRPV1 (0.33) | ALDH1A1MAPTCHRNB4CHRNA3 | |
| SCHEMBL7607284 | 0.61 | CCNT1 (0.50) | CCNT1CDK9JAK2JAK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |